1. Saccharides and Glycosides
  2. Platyconic acid A

Platyconic acid A 

Cat. No.: HY-N9377
Handling Instructions

Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation.

For research use only. We do not sell to patients.

Platyconic acid A Chemical Structure

Platyconic acid A Chemical Structure

CAS No. : 68051-23-0

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Description

Platyconic Acid A is an active component of changkil saponins from platycodon grandiflorum and can be used for the research of reducing airway inflammation[1].

In Vitro

Platyconic Acid A (0.5~2 μM; 30 minutes; A549 cells) inhibits PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner[1].
Platyconic Acid A (0.5~2 μM; 24 hours; A549 cells) decreases PMA-increased MUC5AC mRNA expression in a concentration-dependent manner[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Western Blot Analysis[1]

Cell Line: A549 cells
Concentration: 0.5~2 μM
Incubation Time: 30 minutes
Result: Inhibited PMA-induced NF-κB p65 phosphorylation, IκBα phosphorylation and degradation and Akt phosphorylation in a concentration-dependent manner.

RT-PCR[1]

Cell Line: A549 cells
Concentration: 0.5~2 μM
Incubation Time: 24 hours
Result: Decreased PMA-increased MUC5AC mRNA expression in a concentration-dependent manner.
Molecular Weight

1239.31

Formula

C₅₇H₉₀O₂₉

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Platyconic acid AOthersactiveplatycodongrandiflorumairwayinflammationInhibitorinhibitorinhibit

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Platyconic acid A
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HY-N9377
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