1. Natural Products
  2. Disease Research Fields Plants Terpenoids
  3. Campanulaceae Inflammation/Immunology Triterpenes
  4. Platycodon grandiflorus (Jacq.) A. DC.
  5. Platycoside E

Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice.

For research use only. We do not sell to patients.

Platycoside E Chemical Structure

Platycoside E Chemical Structure

CAS No. : 237068-41-6

Size Price Stock Quantity
1 mg USD 75 In-stock
5 mg USD 190 In-stock
10 mg USD 290 In-stock
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100 mg   Get quote  

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Customer Review

Based on 2 publication(s) in Google Scholar

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Description

Platycoside E is a platycodigenin-type saponin isolated from the root of Platycodon grandiflorum with haemolytic activity and adjuvant potential. Platycoside E promotes the production of the sera OVA-specific IgG2a and IgG2b antibody in the ovalbumin (OVA)-immunized mice[1].

IC50 & Target

IC50: OVA-specific IgG2a and IgG2b antibody[1]

Molecular Weight

1549.60

Formula

C69H112O38

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@H]([C@@H]([C@@H](O[C@@]1([H])[C@@H]([C@H]([C@H](O)CO1)O[C@@]2([H])[C@@H]([C@](CO)(O)CO2)O)O)[C@H](C)O3)O)[C@]3([H])O[C@H]([C@H]([C@@H](O)CO4)O)[C@@H]4OC([C@]56[C@](CC(C)(C)CC6)([H])C7=CC[C@@]([C@@]8([C@@](C(CO)([C@@H](O[C@]9([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]9O)CO[C@@H]%10O[C@@H]([C@@H](O)[C@H](O)[C@H]%10O)CO[C@@H]%11O[C@@H]([C@@H](O)[C@H](O)[C@H]%11O)CO)[C@@H](O)C8)CO)([H])CC%12)C)([H])[C@]%12(C)[C@]7(C)C[C@H]5O)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (64.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6453 mL 3.2266 mL 6.4533 mL
5 mM 0.1291 mL 0.6453 mL 1.2907 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.6453 mL 3.2266 mL 6.4533 mL 16.1332 mL
5 mM 0.1291 mL 0.6453 mL 1.2907 mL 3.2266 mL
10 mM 0.0645 mL 0.3227 mL 0.6453 mL 1.6133 mL
15 mM 0.0430 mL 0.2151 mL 0.4302 mL 1.0755 mL
20 mM 0.0323 mL 0.1613 mL 0.3227 mL 0.8067 mL
25 mM 0.0258 mL 0.1291 mL 0.2581 mL 0.6453 mL
30 mM 0.0215 mL 0.1076 mL 0.2151 mL 0.5378 mL
40 mM 0.0161 mL 0.0807 mL 0.1613 mL 0.4033 mL
50 mM 0.0129 mL 0.0645 mL 0.1291 mL 0.3227 mL
60 mM 0.0108 mL 0.0538 mL 0.1076 mL 0.2689 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Platycoside E
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HY-N3522
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