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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
20 Results for "
Prostaglandin I2
" in MedChemExpress (MCE) Product Catalog:
Products (20)
20 Results for "Prostaglandin I2" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-A0126A
CAS No.: 61849-14-7
Synonyms: Prostaglandin I2 sodium salt; Prostacyclin sodium salt; Flolan
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-P4406
CAS No.: 100307-95-7
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Synonyms: ONO-AP 500-02
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ONO 1301 (ONO-AP 500-02), a prostaglandin (PG) I2 mimetic, is an orally active, long-acting prostacyclin agonist with thromboxane-synthase inhibitory activity. ONO 1301 promotes production of hepatocyte growth factor (HGF) from various cell types and ameliorates ischemia-induced left ventricle dysfunction in the mouse, rat and pig .
Cat. No.: HY-106961A
CAS No.: 153814-74-5
Synonyms: (Z)-ONO-AP 500-02
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(Z)-ONO 1301 is the isomer of ONO 1301 (HY-106961), and can be used as an experimental control. ONO 1301 (ONO-AP 500-02), a prostaglandin (PG) I2 mimetic, is an orally active, long-acting prostacyclin agonist with thromboxane-synthase inhibitory activity. ONO 1301 promotes production of hepatocyte growth factor (HGF) from various cell types and ameliorates ischemia-induced left ventricle dysfunction in the mouse, rat and pig .
Cat. No.: HY-W747129
Synonyms: 15(R)-PGI2 sodium
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15(R)-Prostaglandin I2 (15(R)-PGI2) sodium is a 15(R)-stereoisomer of Epoprostenol (Prostaglandin I2) sodium (HY-A0126A) .
Cat. No.: HY-A0126AR
CAS No.: 61849-14-7
Synonyms: Prostaglandin I2 sodium salt (Standard); Prostacyclin sodium salt (Standard); Flolan (Standard)
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Epoprostenol (sodium) (Standard) is the analytical standard of Epoprostenol (sodium). This product is intended for research and analytical applications. Epoprostenol sodium (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH) . Epoprostenol sodium is used in pulmonary hypertension and transplantation as a potent inhibitor of platelet aggregation .
Cat. No.: HY-180615
CAS No.: 100311-07-7
Synonyms: 15-Dehydro-Prostaglandin I2
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Cat. No.: HY-130594
CAS No.: 62777-90-6
Synonyms: 6α-PGI1
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6α-Prostaglandin I1 (6α-PGI1) is an analogue of prostacycline I2 (PGI2) and is resistant to hydrolysis in aqueous solution .
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AZ-1355 is an orally active and effctive lipid-lowering agent. AZ-1355 inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro .
Cat. No.: HY-124428
CAS No.: 524699-72-7
Synonyms: FK881
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ASP6537 is a potent and selective rhCOX-1 inhibitor with an IC50 of 0.703 nM. ASP6537 has the potential for cardiovascular disease research .
Cat. No.: HY-P4406A
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Cat. No.: HY-106868
CAS No.: 88931-51-5
Synonyms: Isocarbacyclin methyl ester; TEI 9090; TTC 909
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Clinprost (Isocarbacyclin methyl ester; TEI 9090; TTC 909) is a drug preparation of the stable prostaglandin I(2) analogue clinprost incorporated into lipid microspheres. Clinprost can reduce infarct volume in stroke rats .
Cat. No.: HY-129199
CAS No.: 64192-56-9
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U-51605 is a platelet aggregation inhibitor and inhibits thromboxane synthesis. U-51605 is also a prostaglandin I2 synthase inhibitor and can inhibit the retinal vasodilation response induced by NO donors (such as NOR3) .
Cat. No.: HY-130522
CAS No.: 62770-50-7
Synonyms: 6β-PGI1
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6β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID50 (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection) .
Cat. No.: HY-129922
CAS No.: 773825-80-2
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Prostaglandin I2 is an unstable prostanoid which, through the ‘I prostanoid’ (IP) receptor, inhibits platelet aggregation and promotes vasodilatation in pulmonary vascular beds. AFP 07 is a 7,7-difluoroprostacyclin derivative that acts as a selective and highly potent agonist for the IP receptor (Ki=0.561 nM).1 AFP 07 shows weaker affinity for EP receptors, with Ki values > 100 nM for EP1-3 and > 10 nM for EP4. 16(R)-AFP 07 is an epimer of AFP 07. Its biological properties, particularly through the IP and EP receptors, remain to be evaluated.
Cat. No.: HY-133941
CAS No.: 64700-71-6
Synonyms: 2,3-Dinor-6-keto-PGF1α
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Cat. No.: HY-E71198
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15-Hydroxyprostaglandin-I dehydrogenase (NADP+) (EC 1.1.1.231) is specific for prostaglandin I2.
Cat. No.: HY-106961R
CAS No.: 176391-41-6
Synonyms: ONO-AP 500-02 (Standard)
Research Areas:
ONO 1301 (Standard) (ONO-AP 500-02 (Standard)) is the analytical standard of ONO 1301 (HY-106961). This product is intended for research and analytical applications. ONO 1301 (ONO-AP 500-02), a prostaglandin (PG) I2 mimetic, is an orally active, long-acting prostacyclin agonist with thromboxane-synthase inhibitory activity. ONO 1301 promotes production of hepatocyte growth factor (HGF) from various cell types and ameliorates ischemia-induced left ventricle dysfunction in the mouse, rat and pig .
Cat. No.: HY-123366
CAS No.: 70386-06-0
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Y-590 is an orally active platelet cyclic adenosine monophosphate phosphodiesterase (cAMP-PDE) inhibitor with an IC50 of 0.9 nM against rabbit cAMP-PDE. Y-590 inhibits platelet aggregation, disaggregates aggregated platelets, suppresses collagen-induced platelet release, reduces platelet retention and inhibits cAMP degradation in platelets. Y-590 enhances PGI2-mediated elevation of intracellular cAMP in platelets and exerts a synergistic effect with PGI2 on ADP-induced platelet aggregation. Y-590 can be used in studies related to thrombotic diseases and thrombosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
