62770-50-7
Chemical Structure
6β-Prostaglandin I1
Synonym(s): 6β-PGI1
- CAS No.: 62770-50-7
- Formula:C20H34O5
- Molecular Weight:354.48
IUPAC Name: 5-((2S,3aR,4R,5R,6aS)-5-hydroxy-4-((S,E)-3-hydroxyoct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-2-yl)pentanoic acid
InChIKey: RJADQDXZYFCVHV-CBIPHORWSA-N
SMILES: CCCCC[C@H](O)/C=C/[C@@H]1[C@]2([H])[C@@](C[C@H]1O)([H])O[C@H](C2)CCCCC(O)=O
Biological Activity: 6β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID50 (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection)[1].
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6β-Prostaglandin I1 | 6β-Prostaglandin I1 (6β-PGI1) is an analog of prostaglandin I2 (PGI2) that is resistant to hydrolysis in aqueous solutions. 6β-Prostaglandin I1 can reduce gastric acid secretion with an ID50 (dose causing 50% inhibition) of approximately 3.0 μg/kg/min (intravenous injection). | |||||||||||||||||||||
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Keywords
