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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
SCH 23390
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "SCH 23390" in MCE Product Catalog:
Cat. No.: HY-19545
CAS No.: 87075-17-0
Synonyms: R-(+)-SCH-23390
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SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively). SCH-23390 can shorten the latency period for cocaine-induced lever pressing behavior in rats. SCH-23390 can also eliminate generalized seizures caused by chemical convulsants, such as arecoline (HY-B0726A) and strychnine, and is used in research on neurological disorders related to the dopamine system .
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35 Publications Verification
Cat. No.: HY-19545A
CAS No.: 125941-87-9
Synonyms: R-(+)-SCH-23390 hydrochloride
Research Areas:
SCH-23390 hydrochloride (R-(+)-SCH-23390 hydrochloride) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. SCH-23390 hydrochloride is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 hydrochloride also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 hydrochloride inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM .
Cat. No.: HY-108400
CAS No.: 87134-87-0
Synonyms: R-(+)-SCH-23390 maleate
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SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selective dopamine D1-like receptor antagonist with Kis of 0.2 nM and 0.3 nM for the D1 and D5 receptor, respectively. SCH-23390 maleate is a potent and high efficacy human 5-HT2C receptor agonist with a Ki of 9.3 nM. SCH-23390 maleate also binds with high affinity to the 5-HT2 and 5-HT1C receptors. SCH-23390 maleate inhibits G protein-coupled inwardly rectifying potassium (GIRK) channels with an IC50 of 268 nM .
Cat. No.: HY-19545B
CAS No.: 1217443-99-6
Synonyms: SCH-23388 hydrochloride
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(S)-SCH-23390 hydrochloride is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively) .
Cat. No.: HY-D2890
CAS No.: 321862-17-3
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5-TAMRA-NHS is a fluorescent dye composed of 5-TAMRA (HY-15942) and a hydroxysuccinimide (NHS) group. The NHS ester of 5-TAMRA-NHS forms amide bonds with primary amino groups, which is used to construct fluorescently labeled probes and conjugates. The labeled products are suitable for fluorescence anisotropy, confocal imaging and flow cytometry assays. 5-TAMRA-NHS can be used for fluorescent labeling and imaging (Ex/Em = 541/567 nm) .
Cat. No.: HY-111160
CAS No.: 90955-43-4
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SKF 83509, a desmethyl analogue of SCH 23390 (HY-19545A), is a selective dopamine D1 antagonist with a Ki of 70.2 nM. SKF 83509 has no activity at dopamine D2 receptors .
Cat. No.: HY-N15270
CAS No.: 93767-29-4
Synonyms: Secantioquine
Category:
Alkaloids Bisbenzylisoquinoline Alkaloids Plants Annonaceae Pseudoxandra esclerocarpa Maas.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
