2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor
  4. (S)-SCH-23390 hydrochloride

(S)-SCH-23390 hydrochloride  (Synonyms: SCH-23388 hydrochloride)

Cat. No.: HY-19545B Pureza: 99.18% ee.: 99.48%
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(S)-SCH-23390 hydrochloride is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively).

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(S)-SCH-23390 hydrochloride

(S)-SCH-23390 hydrochloride Estructura química

No. CAS : 1217443-99-6

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(S)-SCH-23390 hydrochloride Related Antibodies

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Descripciòn

(S)-SCH-23390 hydrochloride is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with Ki values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively)[1].

In Vivo

(S)-SCH-23390 (0.05-15.5 mg/kg, i.p., single dose) hydrochloride results in no significant reduction of the cerebrospinal fluid (CSF) in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male SD rats (140-200 g)[1]
Dosage: 0.05, 0.5, 5.0 and 15.5 mg/kg
Administration: i.p., single dose
Result: Did not significantly reduce the net production of CSF at any dose between 0.05 and 15.5 mg/kg.
Peso molecular

324.24

Fòrmula

C17H19Cl2NO
No. CAS
Appearance

Powder

Color

off-white

SMILES

OC1=C(Cl)C=C2CCN(C)C[C@@H](C3=CC=CC=C3)C2=C1.[H]Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

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Referencias
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(S)-SCH-23390 hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(S)-SCH-233901217443-99-6SCH-23388SCH23388SCH 23388Dopamine ReceptorS-enantiomerCSFratSCH-23390Inhibitorinhibitorinhibit

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Nombre del producto:
(S)-SCH-23390 hydrochloride
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HY-19545B
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