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Cat. No.: HY-19545B

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(S)-SCH-23390 hydrochloride

(Synonyms: SCH-23388 hydrochloride)

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Based on 1 Customer Validation

(S)-SCH-23390 hydrochloride is the S-enantiomer of SCH-23390 (HY-19545). SCH-23390 is a dopamine D1-like receptor antagonist (with K_i values of 0.2 nM and 0.3 nM for the D1 and D5 receptor subtypes, respectively).

For research use only. We do not sell to patients.

Purity: 99.18%
CAS No.: 1217443-99-6
Formula: C₁₇H₁₉Cl₂NO
Molecular Weight:324.24

Storage:

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

(S)-SCH-23390 hydrochloride Chemical Structure

CAS No.: 1217443-99-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

All Dopamine Receptor Isoforms :

In Vivo

(S)-SCH-23390 (0.05-15.5 mg/kg, i.p., single dose) hydrochloride results in no significant reduction of the cerebrospinal fluid (CSF) in rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Male SD rats (140-200 g)^[1]
Dosage:

0.05, 0.5, 5.0 and 15.5 mg/kg
Administration:

i.p., single dose
Result:

Did not significantly reduce the net production of CSF at any dose between 0.05 and 15.5 mg/kg.

Chemical Information

CAS No. 1217443-99-6
Appearance Powder
Molecular Weight 324.24
Formula C₁₇H₁₉Cl₂NO
Color off-white
SMILES

OC1=C(Cl)C=C2CCN(C)C[C@@H](C3=CC=CC=C3)C2=C1.[H]Cl
Synonyms

SCH-23388 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Boyson SJ, et al. Net production of cerebrospinal fluid is decreased by SCH-23390. Ann Neurol. 1990 Jun;27(6):631-5. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References

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(S)-SCH-23390 hydrochloride

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(S)-SCH-23390 hydrochloride

Bioactive Compound Library Max

Bioactive Compound Library

GPCR/G Protein Compound Library

Neuronal Signaling Compound Library

Neurotransmitter Receptor Compound Library

Neurodegenerative Disease-related Compound Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Dopamine Receptor Compound Library

MCE Bioactive Compound Library

High-Throughput Bioactive Compound Library

Lactylation Compound Library

All Dopamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(S)-SCH-23390 hydrochloride Related Classifications

HY-19545B Related Classifications