4 Results for "

SU-5416

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "SU-5416" in MCE Product Catalog:

81
81 Cited Publications
Cat. No.: HY-10374
CAS No.: 204005-46-9
Purity:  99.96%
Synonyms: SU5416
Target:  

VEGFR

Semaxinib (SU5416) is a potent and selective inhibitor of VEGFR (Flk-1/KDR) with an IC50 of 1.23 μM .
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4
4 Cited Publications
Cat. No.: HY-10332
CAS No.: 194413-58-6
Synonyms: (Z)-SU5416
Target:  

VEGFR

(Z)-Semaxanib ((Z)-SU5416) is a VEGF receptor tyrosine kinase inhibitor that blocks VEGF signaling through Flk-1/KDR. (Z)-Semaxanib inhibits angiogenesis by preventing new blood vessel formation. (Z)-Semaxanib induces cytotoxicity in liver cancer cells. (Z)-Semaxanib can be used in research on metastatic renal cell carcinoma, gastrointestinal stromal tumors, well-differentiated pancreatic neuroendocrine tumors, and solid tumors .
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Cat. No.: HY-113953
CAS No.: 153088-73-4
Purity:  99.64%
Target:  

Caspase Apoptosis

Research Areas:  

Inflammation/Immunology

Z-Asp-CH2-DCB is an irreversible broad spectrum caspase inhibitor. Z-Asp-CH2-DCB also inhibits proteases with caspase-like activity. Z-D-CH2-DCB blocks the production of IL-1β, TNF-α, IL-6, and IFN-γ in staphylococcal enterotoxin B (SEB)-stimulated peripheral blood mononuclear cells (PBMC), and reduces SEB-1-stimulated T-cell proliferation in a dose-dependent manner. Z-Asp-CH2-DCB prevents SU5416-induced septal cell apoptosis and emphysema development .
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Cat. No.: HY-10374R
CAS No.: 204005-46-9
Synonyms: SU5416 (Standard)
Research Areas:  

Cancer

Semaxinib (Standard) is the analytical standard of Semaxinib (HY-10374). This product is intended for research and analytical applications. Semaxinib (SU5416) is a potent and selective inhibitor of VEGFR (Flk-1/KDR) with an IC50 of 1.23 μM .
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