34 Results for "

SUMO protease

" in MedChemExpress (MCE) Product Catalog:
Products (34)

34 Results for "SUMO protease" in MCE Product Catalog:

Cat. No.: HY-E70372
CAS No.: 1607459-82-4
Research Areas:  

Others

SUMO Protease is highly specific for proteins containing small ubiquitin-like modifier (SUMO) tags. SUMO Protease can be used to regulates the proteins splicing, controlls protein structure and function in vitro .
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7
7 Publications Verification
Cat. No.: HY-N2360
CAS No.: 19202-36-9
Hinokiflavone is a novel modulator of pre-mRNA splicing activity extracted from plants with anti-inflammatory, anti-tumor and antiviral activities. Hinokiflavone is also a potent inhibitor for matrix metalloproteinases (MMPs). Hinokiflavone attenuates the virulence of Methicillin (HY-121544)-resistant staphylococcus aureus by inhibiting caseinolytic protease P (ClpP) with an IC50 value of 34.36 mg/mL. Hinokiflavone induces apoptosis via the reactive oxygen species-mitochondria-mediated apoptotic pathway and inhibits tumor cell migration and invasion. Hinokiflavone is a SUMO protease inhibitor against sentrin-specific protease 1 (SENP1) activity .
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5
5 Cited Publications
Cat. No.: HY-N0330
CAS No.: 96990-18-0
Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
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2
2 Cited Publications
Cat. No.: HY-103435
CAS No.: 858134-23-3
Purity:  99.90%
Synonyms: Terrestrin A
Vialinin A (Terrestrin A) is a p-terphenyl compound that can be derived from a Chinese edible mushroom. Vialinin A is an inhibitor of ubiquitin-specific peptidase 4 (USP4) and has anti-inflammatory and antioxidant properties. Vialinin A can alleviate cerebral ischaemia-reperfusion injury-induced neurological deficits and neuronal apoptosis. Vialinin A promotes activation of Keap1-Nrf2-ARE signaling pathway and increases the protein degradation of Keap1. Vialinin A possesses various pharmacological activities in cancer, Kawasaki disease, asthma, and pathological scarring. Vialinin A is a potent inhibitor of TNF-α, USP4, USP5, and sentrin/SUMO-specific protease 1 (SENP1). Vialinin A can be studied in reseach for autoimmune diseases, cancer and ischaemic stroke .
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1
1 Cited Publications
Cat. No.: HY-134594
CAS No.: 2416910-69-3
Purity:  99.55%
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

SENP1-IN-1 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 29. SENP1-IN-1 is developed for tumor radiosensitivity enhancement .
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1
1 Cited Publications
Cat. No.: HY-P72155
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CTSD; Cathepsin D (Lysosomal Aspartyl protease); Prev. CPSD; Lysosomal Aspartyl protease; CLN10; Cathepsin D Isoform 2; Ceroid-Lipofuscinosis, Neuronal 10; HEL-S-130P; Epididymis Secretory Sperm Binding Protein Li 130P; Cathepsin D; Lysosomal Aspartyl Pep
Species:  
Others
Source:  
E. coli
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Cat. No.: HY-134596
CAS No.: 2416910-59-1
Purity:  99.92%
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement .
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Cat. No.: HY-W342380
CAS No.: 5463-64-9
Synonyms: NSC 5067
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM). SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression .
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Cat. No.: HY-134597
CAS No.: 2416910-64-8
Purity:  ≥98.0%
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

SENP1-IN-4 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 21. SENP1-IN-4 is developed for tumor radiosensitivity enhancement .
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Cat. No.: HY-N2360R
CAS No.: 19202-36-9
Hinokiflavone is a novel modulator of pre-mRNA splicing activity extracted from plants with anti-inflammatory, anti-tumor and antiviral activities. Hinokiflavone is also a potent inhibitor for matrix metalloproteinases (MMPs). Hinokiflavone attenuates the virulence of Methicillin (HY-121544)-resistant staphylococcus aureus by inhibiting caseinolytic protease P (ClpP) with an IC50 value of 34.36 mg/mL. Hinokiflavone induces apoptosis via the reactive oxygen species-mitochondria-mediated apoptotic pathway and inhibits tumor cell migration and invasion. Hinokiflavone is a SUMO protease inhibitor against sentrin-specific protease 1 (SENP1) activity .
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Cat. No.: HY-134595
CAS No.: 2416910-70-6
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

SENP1-IN-2 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 30. SENP1-IN-2 is developed for tumor radiosensitivity enhancement .
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Cat. No.: HY-P701239AF
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SUMO protease
Species:  
Others
Source:  
E. coli
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Cat. No.: HY-N0330R
CAS No.: 96990-18-0
Momordin Ic (Standard) is the analytical standard of Momordin Ic. This product is intended for research and analytical applications. Momordin Ic is an orally active triterpenoid saponin that can be isolated from Kochia scoparia. It is also a SUMO specific protease 1 (SENP1) inhibitor, SENP1/c-MYC signaling pathway inhibitor, and apoptosis inducer. Momordin Ic induces autophagy and apoptosis in liver cancer cells through the PI3K/Akt and MAPK signaling pathways mediated by reactive oxygen species. Momordin Ic has the ability to control glucose induced blood glucose elevation, inhibit gastric emptying, resist rheumatoid arthritis, reduce CCl4 (HY-Y0298) induced hepatotoxicity and anti-tumor activity .
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Cat. No.: HY-P71289
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SENP7; SUMO1/Sentrin Specific Peptidase 7; SUMO Specific Peptidase 7; SUMO1/Sentrin Specific protease 7; Sentrin/SUMO-Specific protease SENP7; KIAA1707; Sentrin-Specific protease 7; SUSP2; SUMO-1-Specific protease 2; SSP2
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701473
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SENP6; SUMO1/Sentrin Specific protease 6; SUMO Specific Peptidase 6; Sentrin-Specific protease 6; SUSP1; SUMO-1-Specific protease 1; KIAA0797; SSP1; Sentrin/SUMO-Specific protease SENP6; Alternative Protein SENP6; SUMO1/Sentrin Specific Peptidase 6; 28100
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P701472
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SENP6; SUMO1/Sentrin Specific protease 6; SUMO Specific Peptidase 6; Sentrin-Specific protease 6; SUSP1; SUMO-1-Specific protease 1; KIAA0797; SSP1; Sentrin/SUMO-Specific protease SENP6; Alternative Protein SENP6; SUMO1/Sentrin Specific Peptidase 6; 28100
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P702804
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SENP6; SUMO1/Sentrin Specific protease 6; SUMO Specific Peptidase 6; Sentrin-Specific protease 6; SUSP1; SUMO-1-Specific protease 1; KIAA0797; SSP1; Sentrin/SUMO-Specific protease SENP6; Alternative Protein SENP6; SUMO1/Sentrin Specific Peptidase 6; 28100
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P79459
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SENP1; SUMO1/Sentrin Specific protease 1; SUMO Specific Peptidase 1; Sentrin-Specific protease 1; Sentrin/SUMO-Specific protease SENP1; SuPr-2; SUMO1/Sentrin Specific Peptidase 1
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-P705923
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SENP5; SUMO1/Sentrin Specific protease 5; SUMO Specific Peptidase 5; Sentrin-Specific protease 5; Sentrin/SUMO-Specific protease SENP5; MGC27076; SUMO1/Sentrin Specific Peptidase 5; SUMO1/Sentrin Specific Peptidase 5, Isoform CRA_a
Species:  
Human
Source:  
Sf9 insect cells
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Cat. No.: HY-P810983
Synonyms: SSP3, SUSP3, SENP3, Sentrin-specific protease 3, SUMO-1-specific protease 3, Sentrin/SUMO-specific protease SENP3

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Monkey

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