1. Metabolic Enzyme/Protease
  2. E1/E2/E3 Enzyme
  3. SENP1-IN-3

SENP1-IN-3 

Cat. No.: HY-134596
Handling Instructions

SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement.

For research use only. We do not sell to patients.

SENP1-IN-3 Chemical Structure

SENP1-IN-3 Chemical Structure

CAS No. : 2416910-59-1

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Description

SENP1-IN-3 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 17. SENP1-IN-3 is developed for tumor radiosensitivity enhancement[1].

IC50 & Target

SENP1[1]

In Vitro

SENP1-IN-3 improves the sensitivity of tumor cells to irradiation[1].
SENP1-IN-3 (0.7-20 μM; 72 hours)has cytotoxic for Hella cells with an IC50 of >20μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: Hela cells
Concentration: 0.7 μM, 2.2 μM, 6.6 μM, 20 μM
Incubation Time: 72 hours
Result: IC50>20 μM
Molecular Weight

582.86

Formula

C₃₆H₅₈N₂O₄

CAS No.

2416910-59-1

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

SENP1-IN-3E1/E2/E3 EnzymeE1 activating enzymeE2 conjugating enzymeE3 ligating enzymeUbiquitin activating enzymeUbiquitin conjugating enzymeUbiquitin ligasespecificdeSUMOylationproteaseSENP1tumorradiosensitivityenhancementradiosensitizersmallubiquitin-like modifierSUMOInhibitorinhibitorinhibit

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SENP1-IN-3
Cat. No.:
HY-134596
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