SENP1-IN-2
SENP1-IN-2 is a specific deSUMOylation protease 1 (SENP1) inhibitor extracted from patent CN110627860, Compound 30. SENP1-IN-2 is developed for tumor radiosensitivity enhancement.
For research use only. We do not sell to patients.
- CAS No.: 2416910-70-6
- Formula: C36H60N2O5
- Molecular Weight:600.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SENP1[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>20 μM
Compound: 43
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Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
Cytotoxicity against human HeLa cells assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay
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[PMID: 34688014] |
SENP1-IN-2 may improve the sensitivity of tumor cells to irradiation[1].
SENP1-IN-2 (0.7-20 μM; 72 hours) has cytotoxic for Hella cells with an IC50 of >20 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Hela cells
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Concentration:0.7 μ M, 2.2 μM, 6.6 μM, 20 μM
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Incubation Time:72 hours
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Result:IC50>20 μM
Chemical Information
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CAS No. 2416910-70-6
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Molecular Weight 600.87
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Formula C36H60N2O5
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SMILES
CC1(C)[C@@H](O)CC[C@]2(C)[C@@]3([H])CC=C4[C@]5([H])[C@@H](C)[C@H](C)CC[C@@](C(NCC(N(CCO)CCO)=O)=O)5CC[C@](C)4[C@@](C)3CC[C@@]12[H]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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