5463-64-9
5463-64-9
Chemical Structure
SPI-05
Synonym(s): NSC 5067
- CAS No.: 5463-64-9
- Formula:C34H26N6O6S2
- Molecular Weight:678.74
IUPAC Name: 5-((E)-(4-aminonaphthalen-1-yl)diazenyl)-2-((E)-4-((E)-(4-aminonaphthalen-1-yl)diazenyl)-2-sulfostyryl)benzenesulfonic acid
InChIKey: BEOHKTZPLVXCFG-NKPXSSHVSA-N
SMILES: NC1=CC=C(C2=C1C=CC=C2)/N=N/C(C=C3)=CC([S](=O)(O)=O)=C3/C=C/C(C=CC(/N=N/C(C4=C5C=CC=C4)=CC=C5N)=C6)=C6[S](=O)(O)=O
Biological Activity: SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM). SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression[1].
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SPI-05 | SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM). SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression. | |||||||||||||||||||||
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