5463-64-9

SPI-05 Chemical Structure
5463-64-9

Chemical Structure

SPI-05

Synonym(s): NSC 5067

  • CAS No.: 5463-64-9
  • Formula:C34H26N6O6S2
  • Molecular Weight:678.74

IUPAC Name: 5-((E)-(4-aminonaphthalen-1-yl)diazenyl)-2-((E)-4-((E)-(4-aminonaphthalen-1-yl)diazenyl)-2-sulfostyryl)benzenesulfonic acid

InChIKey: BEOHKTZPLVXCFG-NKPXSSHVSA-N

SMILES: NC1=CC=C(C2=C1C=CC=C2)/N=N/C(C=C3)=CC([S](=O)(O)=O)=C3/C=C/C(C=CC(/N=N/C(C4=C5C=CC=C4)=CC=C5N)=C6)=C6[S](=O)(O)=O

Biological Activity: SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM). SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression[1].

Cat. No. Product Name Purity Description Pricing
HY-W342380
SPI-05 SPI-05 (NSC 5067) is a non-competitive SUMO-specific proteases (SENP1/2) inhibitor (IC50=60 μM). SPI-05 is promising for research of cancers, such as prostate cancer and hypoxia-driven solid tumors with SENP1 overexpression.
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