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Sestrin2-GATOR2 binding assay

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W074912
    (S)-2-Amino-5,5,5-trifluoropentanoic acid

    (S)-5,5,5-Trifluoronorvaline; H-Nva(5,5,5-triF)-OH

    		 mTOR Neurological Disease Metabolic Disease Cancer
    (S)-2-Amino-5,5,5-trifluoropentanoic acid ((S)-5,5,5-Trifluoronorvaline; H-Nva (5,5,5-triF)-OH) is a selective Sestrin-GATOR2 modulator that indirectly inhibits mTORC1 activity via a competitive binding mechanism. (S)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on cancer, metabolic diseases, neurodegenerative diseases, and muscle atrophy .\n
    (S)-2-Amino-5,5,5-trifluoropentanoic acid

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