122565-28-0
122565-28-0
Chemical Structure
(S)-2-Amino-5,5,5-trifluoropentanoic acid
Synonym(s): (S)-5,5,5-Trifluoronorvaline; H-Nva(5,5,5-triF)-OH
- CAS No.: 122565-28-0
- Formula:C5H8F3NO2
- Molecular Weight:171.12
IUPAC Name: (S)-2-amino-5,5,5-trifluoropentanoic acid
InChIKey: KTZZIDWVKLDWBF-VKHMYHEASA-N
SMILES: C([C@@H](C(O)=O)N)CC(F)(F)F
Biological Activity:
(S)-2-Amino-5,5,5-trifluoropentanoic acid ((S)-5,5,5-Trifluoronorvaline; H-Nva (5,5,5-triF)-OH) is a selective Sestrin-GATOR2 modulator that indirectly inhibits mTORC1 activity via a competitive binding mechanism. (S)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on cancer, metabolic diseases, neurodegenerative diseases, and muscle atrophy[1].\n
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(S)-2-Amino-5,5,5-trifluoropentanoic acid | (S)-2-Amino-5,5,5-trifluoropentanoic acid ((S)-5,5,5-Trifluoronorvaline; H-Nva (5,5,5-triF)-OH) is a selective Sestrin-GATOR2 modulator that indirectly inhibits mTORC1 activity via a competitive binding mechanism. (S)-2-Amino-5,5,5-trifluoropentanoic acid can be used in research on cancer, metabolic diseases, neurodegenerative diseases, and muscle atrophy.\n |
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