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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
Sialyltransferase Inhibitors
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "Sialyltransferase Inhibitors" in MCE Product Catalog:
5
5 Cited Publications
Target:
Research Areas:
3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
3
3 Cited Publications
Synonyms: CMP-Neu5Ac sodium salt
Target:
Category:
Human Gut Microbiota Metabolites Natural Products Metabolic Disease Endogenous metabolite Disease Research Fields
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Synonyms: α-2,3-Sialyltransferase-IN-1
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(R)-Lith-O-Asp (α-2,3-Sialyltransferase-IN-1) is a noncompetitive α-2,3-sialyltransferase inhibitor with an IC50 of 6 μM.
Cat. No.: HY-E70299
Synonyms: ST3GAL5
Target:
Research Areas:
ST3 β-Gal α-2,3-Sialyltransferase 5 (ST3GAL5) is a glycosphingolipid (GSL) biosynthetic enzyme that can inhibit TGF-β-induced epithelial-mesenchymal transition (EMT), invasion, and metastasis both in vivo and in vitro. ST3 β-Gal α-2,3-Sialyltransferase 5 can be used in cancer research .
Cat. No.: HY-137985
CAS No.: 149598-70-9
Synonyms: Stachybotrydial; F 1839M; Stachybotrydial
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Research Areas:
Mer-NF5003F (Stachybotrydial; F 1839M), a sesquiterpene isolated from Stachybotrys, inhibits avian medulloblastoma virus (AMV) protease (IC50=7.8 μM). Mer-NF5003F inhibits sialyltransferase 6N (ST6N), ST3O, and ST3N (IC50=0.61, 6.7, and 10 μg/mL, respectively), and fucosyltransferase (IC50=11.3 μg/mL). Mer-NF5003F has in vitro activity against herpes simplex virus HSV-1 (IC50=4.32 μg/mL) and multidrug-resistant Plasmodium falciparum K1 strain (IC50=0.85 μg/mL).
Cat. No.: HY-110288R
CAS No.: 117405-58-0
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Research Areas:
3FAx-Neu5Ac (Standard) is the analytical standard of 3FAx-Neu5Ac (HY-110288). This product is intended for research and analytical applications. 3FAx-Neu5Ac (Compound 8), a Sialic acid peracetylated analog, is a sialyltransferase inhibitor. 3FAx-Neu5Ac substantially reduces expression of the sialylated ligand sialyl Lewis X .
Cat. No.: HY-112942B
CAS No.: 149007-28-3
Synonyms: CMP-Neu5Ac disodium
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Research Areas:
CMP-Sialic acid (CMP-Neu5Ac) sodium is an allosteric inhibitor of UDP-GlcNAc 2-epimerase. CMP-Sialic acid sodium provides a substrate for Golgi sialyltransferases. CMP-Sialic acid sodium is an important sugar nucleotide for biosynthesis of sialic acid and its conjugates .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
