5 Results for "

T cell leukaemia

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "T cell leukaemia" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-14174
CAS No.: 677772-84-8
Purity:  99.51%
Target:  

γ-secretase

Research Areas:  

Neurological Disease Cancer

MRK-560, a chemical probe, is an orally active, brain barrier-penetrated γ-Secretase inhibitor, reducing Aβ peptide in rat brain and cerebrospinal fluid. MRK-560 decreases mutant NOTCH1 processing by selectively inhibiting PSEN1. MRK-560 can be used in studies of Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL) .
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Cat. No.: HY-P9948
CAS No.: 216503-57-0
Synonyms: Campath-IH

Target:  

Apoptosis

Research Areas:  

Cancer

Alemtuzumab (Campath-IH) is a humanized monoclonal antibody against CD52. Alemtuzumab does not cross-react with murine CD52. Alemtuzumab selectively targets the CD52 antigen to induce profound lymphocyte depletion, followed by recovery of T and B cells with regulatory phenotypes. Alemtuzumab is capable of complement-dependent cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC), as well as induction of apoptosis. Alemtuzumab has the potential for B-cell chronic lymphocytic leukaemia research .
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Cat. No.: HY-P99390
CAS No.: 2044679-53-8
Synonyms: MCLA 117
Tepoditamab (MCLA-117) is a full-length human IgG1 bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells. Tepoditamab induces upto 30-fold T-cell expansion. Tepoditamab results in moderate to strong cytokine (IFNγ, IL-6, IL-8, IL-10, and TNFα) and IFNγ release in human whole blood and PBMC, respectively. Tepoditamab can be used in acute myeloid leukaemia (AML) research .
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Cat. No.: HY-145866
Target:  

Drug Intermediate

Research Areas:  

Cancer

Antiproliferative agent-3 is an antiproliferative agent. Antiproliferative agent-3 exhibits anticancer activity against a variety of cancers, including estrogen receptor-positive breast cancer. Antiproliferative agent-3 shows no toxicity to wild-type zebrafish embryos. Antiproliferative agent-3 can be used in the research of chronic myeloid leukemia, promyelocytic leukemia, Burkitt's lymphoma, estrogen receptor-positive mammary adenocarcinoma, cervical cancer, and lung cancer .
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Cat. No.: HY-P11435
CAS No.: 164031-33-8
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

KQSSKALQR is a BCR-ABL peptide. KQSSKALQR can induce CD8 +T cell responses. KQSSKALQR can be used in vaccine research for chronic myeloid leukaemia (CML) .
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