4 Results for "

TA102

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "TA102" in MCE Product Catalog:

Cat. No.: HY-W015940
CAS No.: 1455-77-2
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection Cancer

Guanazole is a ribonucleotide reductase (RNR) inhibitor that blocks replicative DNA synthesis by inhibiting deoxyribonucleotide biosynthesis. Guanazole selectively inhibits DNA synthesis in rapidly proliferating tissues, induces replication stress and G2/M phase arrest in Schizosaccharomyces pombe, and exhibits myelosuppressive, immunosuppressive, and anti-L1210 leukemia activities. Guanazole does not induce DNA repair and only shows slight mutagenicity towards Salmonella typhimurium TA102. Guanazole serves as an alternative tool to Hydroxyurea (HY-B0313) for replication checkpoint studies in Schizosaccharomyces pombe. Guanazole can be applied in research related to leukemia and solid tumors .
loading...
    loading...
Cat. No.: HY-163292
CAS No.: 3029324-01-1
Target:  

Bacterial Parasite

Research Areas:  

Infection

Antibacterial agent 180 (15g), an appropriate substrate for the type I nitro reductases (TcNTR I), is a promising antitrypanosomatid agent. Antibacterial agent 180 (15g) shows nonmutagenic potential against Salmonella typhimurium strains (TA98, TA100, and TA102) .
loading...
    loading...
Cat. No.: HY-W010553
CAS No.: 14400-67-0
Synonyms: 2,5-Dimethyl-2,3-dihydrofuran-3-one
Research Areas:  

Infection

2,5-Dimethyl-3 (2H)-furanone (2,5-dimethyl-2,3-dihydrofuran-3-one) is an α,β-unsaturated 3 (2H)-furanone flavoring substance. 2,5-Dimethyl-3 (2H)-furanone does not show mutagenic activity in S. typhimurium .
loading...
    loading...
Cat. No.: HY-W587784
CAS No.: 542-40-5
Norbixin is an orally active natural product with multiple activities such as retinal protection and oxidative stress regulation. Norbixin scavenges ROS, chelates metal ions, regulates plasmid and genomic DNA breakage, inhibits H2O2-induced mutagenesis, activates PPAR-α, modulates lipid levels, restores or regulates antioxidant enzyme activity, and alters NO levels. Norbixin prevents A2E accumulation and protects photoreceptor cells and retinal pigment epithelial cells. Norbixin is a derivative of Bixin (HY-N6884). Norbixin can be used in research related to diseases such as macular degeneration and diabetes, and also serves as a natural textile dye .
loading...
    loading...