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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
TREM2；human IgG1
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "TREM2；human IgG1" in MCE Product Catalog:
Cat. No.: HY-P990043
CAS No.: 2733621-19-5
Synonyms: VGL101
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Cat. No.: HY-P991442
Synonyms: TAK-920
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Cat. No.: HY-P991174
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Cat. No.: HY-P992118
CAS No.: 3056296-07-9
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Cat. No.: HY-P991734A
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VHB937 (IgG1-LALA) is a derivative of VHB937 (HY-P991734). VHB937 is a human monoclonal antibody that acts as a potent and selective TREM2 agonist. VHB937 enhances the surface expression of TREM2 and its downstream signaling pathways, such as Syk phosphorylation and calcium mobilization. VHB937 has demonstrated significant neuroprotective effects in various animal models of neuroinflammation and neurodegeneration, effectively alleviating pathological damage and reducing pro-inflammatory marker levels. VHB937 can be used in research related to neurodegenerative diseases.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
