Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
Thiosemicarbazones
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "Thiosemicarbazones" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: Block lipid transport-1
Target:
Research Areas:
BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .
1
Cat. No.: HY-W291131
CAS No.: 27830-79-1
Synonyms: IBT
Target:
Research Areas:
Isatin-β-thiosemicarbazone is a potent anti-poxvirus agent (including monkeypox virus, orthopoxvirus, vaccinia virus, etc). Isatin-β-thiosemicarbazone also is a potent herpes simplex virus (HSV) inhibitor. Isatin-β-thiosemicarbazone exhibits
Synonyms: HI-6
Target:
Research Areas:
Asoxime dichloride (HI-6) is an orally active thiosemicarbazone-based antidote. Asoxime dichloride is a reversible inhibitor of AChE, and its core mechanism of action is to re-activate AChE inhibited by nerve toxins, thereby restoring the cholinergic nerve function. Asoxime dichloride significantly restores the function of poisoned muscles without reactivating AChE. Asoxime dichloride is an antagonist of acetylcholine receptors (AChRs), including nicotinic receptor and α7 nAChR. Asoxime dichloride can serve as an effective immunomodulator, improving the immune effect of the nervous system .
Cat. No.: HY-P1726
CAS No.: 1416983-77-1
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Target:
Research Areas:
BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM. BVDV-IN-1 directly binds to a hydrophobic pocket of the BVDV RdRp. BVDV-IN-1 has antiviral activity against BVDV resistant to NNI thiosemicarbazone (TSC) .
Cat. No.: HY-P0077
CAS No.: 1190083-57-8
Target:
Research Areas:
Cat. No.: HY-P1726A
Target:
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Cat. No.: HY-P0041A
Target:
Research Areas:
Cat. No.: HY-158743
CAS No.: 2345755-20-4
Target:
Research Areas:
Indium (III) thiosemicarbazone 5b (compound 5b) is an Indium (III) thiosemicarbazone agent. Indium (III) thiosemicarbazone 5b effectively inhibits MCF-7 and DDP tumor cells growth .
Cat. No.: HY-151495
Target:
Research Areas:
CAII-IN-3 (compound 3h), a thiosemicarbazones derivatives, is a potent carbonic anhydrase-II (CA-II) inhibitor with an IC50 value of 13.4 µM .
Cat. No.: HY-163448
Target:
Research Areas:
NPP1-IN-2 (compound 3h) is a potent and selective Ectonucleotide pyrophosphatase/phosphodiesterase-1 (NPP1) inhibitor with IC50 values of 0.55, 3.73 µM for NPP1, NPP3, respectively .
Cat. No.: HY-163664
CAS No.: 3040385-73-4
Target:
Research Areas:
Tubulin polymerization-IN-63 (compound 6) is a tubulin polymerization inhibitor. The IC50 value of Tubulin polymerization-IN-63 for MES-SA cells is 0.29 μM. Tubulin polymerization-IN-63 can be used in cancer research .
Cat. No.: HY-P2331
CAS No.: 59165-34-3
Synonyms: Antibiotic A 3802-IV-3; Gardimycin
Target:
Research Areas:
Cat. No.: HY-P10014
CAS No.: 153507-46-1
Target:
Research Areas:
Cat. No.: HY-P0041
CAS No.: 162277-99-8
Target:
Research Areas:
Cat. No.: HY-141425
CAS No.: 79560-74-0
Target:
Research Areas:
NSC73306, a thiosemicarbazone, is a cell penetrant, cytotoxic agent that exhibits greater toxicity against cells expressing functional P-gp (P-glycoprotein) than against other cells .
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
