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Trichophyton mentagrophytes

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bacterial (5) Fungal (11) Insecticide (1) Leukotriene Receptor (1) NO Synthase (1) Parasite (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Cancer (3) Infection (13) Inflammation/Immunology (3)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1133

Sulbentine 1 Publications Verification Dibenzthione	Fungal	Infection
Sulbentine (Dibenzthione) is a thiadiazine-class antifungal agent. Sulbentine exhibits fungicidal and fungistatic activity against Trichophyton mentagrophytes. Sulbentine can be used for the research of dermatophyte infection .

HY-N3968

Goniothalamin GTN; (R)-(+)-Goniothalamin	Apoptosis Insecticide Bacterial Fungal Reactive Oxygen Species (ROS)	Infection Inflammation/Immunology Cancer
Goniothalamin (GTN) is a styryl lactone. Goniothalamin exhibits insecticidal, anti-tumor and antibacterial activities. Goniothalamin induces cell cycle arrest and apoptosis in tumor cells. Goniothalamin acts as a larvicide against Culex quinquefasciatus larvae and as a cytotoxin against brine shrimp larvae. Goniothalamin functions as an antibacterial agent against Gram-positive and Gram-negative bacteria, and also acts as an antifungal agent against pathogens including Candida albicans, Trichophyton rubrum and Trichophyton mentagrophytes. Goniothalamin is applicable to research related to breast cancer, lymphatic filariasis, bacterial infections and fungal infections .

HY-W587956

α-Guaiene	Fungal	Infection
α-Guaiene is a natural sesquiterpene and fungicidal agent found in Pogostemon cablin (patchouli) essential oil. α-Guaiene suppresses the growth of Aspergillus niger, Candida albicans, Microsporum gypseum, and Trichophyton mentagrophytes. α-Guaiene can be used for the study of fungal infection .

HY-N15640

Filiformin (-)-Filiformin	Bacterial	Infection Inflammation/Immunology Cancer
Filiformin ((-)-Filiformin) is a sesquiterpene compound that can be isolated from Laurencia filiformis forma heteroclada. Filiformin exhibits certain cytotoxicity against P388 and BSC-1 cells. Filiformin has antimicrobial activity against Bacillus subtilis, Trichophyton mentagrophytes and Candida albicans. In addition, Filiformin can inhibit oxygen uptake in isolated rat liver mitochondria at a concentration of 150 μM .

HY-106472

Tioxaprofen EMD 26644	Bacterial	Infection
Tioxaprofen is a new anti-mycotic drug against Trichophyton mentagrophytes and T. rubrum, and is a potent uncoupling agent of mitochondrial respiration .

HY-138050

Nyasol (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol	NO Synthase Bacterial Fungal Parasite Leukotriene Receptor	Infection Inflammation/Immunology
Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .

HY-N11434

Anisocoumarin H	Fungal	Infection
Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL .

HY-N15048

Phellinsin	Fungal	Infection
Phellinsin selectively inhibits the activity of the chitin synthase I and II with IC₅₀s (μg/mL) of 76 and 28, respectively. Phellinsin has the antifungal activity on Colletotrichum lagenarium, Pyricularia oryzae, Aspergillus fumigatus and Trichophyton mentagrophytes and so on (MIC is 12.5-50 μg/mL) .

HY-129339

Akrobomycin	Fungal	Infection Cancer
Akrobomycin is an anthracycline antibiotic. Akrobomycin shows antimicrobial and antitumor activities .

HY-N17734

2-Deethoxy-2-hydroxyphantomolin	Bacterial Fungal	Infection
2-Deethoxy-2-hydroxyphantomolin, Germacranolide, is an Antifungal and Antibacterial agent. 2-Deethoxy-2-hydroxyphantomolin can be isolated from Elephantopus tomentosus Linn and E. mollis. 2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone) and slightly active against Escherichia coli (12 mm), Pseudomonas aeruginosa (12 mm), Bacillus subtilis (14 mm), and Trichophyton mentagrophytes (13 mm) .

HY-N14524

Gladiolic acid	Fungal	Infection
Gladiolic acid has the antifungal activity of Absidia glauca Hagem, garlic spores, Byssochlamys fulva, Trichophyton mentagrophytes, Corpuscular falciparum .

HY-W069116

Antifungal agent 146	Fungal	Infection
Antifungal agent 146 (Compound 19l) is a broad-spectrum antifungal agent. Antifungal agent 146 has inhibitory effects on the main dermatophytes that cause onychomycosis (Trichophyton rubrum, Trichophyton mentagrophytes) and other fungi (Candida albicans, Cryptococcus neoformans and Aspergillus fumigatus) with MIC values of 16, 16, 64, 32, and 32 μg/mL. Antifungal agent 146 can be used for the research of infection .

HY-N19881

Drimenal	Fungal	Infection
Drimenal is a pimarane-type natural sesquiterpene with antifungal activity. Drimenal inhibits the growth of yeasts and dermatophytes. Drimenal can be used for the development of pesticide candidates and in research related to fungal infections .

Goniothalamin GTN; (R)-(+)-Goniothalamin	Structural Classification Natural Products Lythraceae Plants Lythrum salicaria L. Source Classification	Apoptosis Insecticide Bacterial Fungal Reactive Oxygen Species (ROS)
Goniothalamin (GTN) is a styryl lactone. Goniothalamin exhibits insecticidal, anti-tumor and antibacterial activities. Goniothalamin induces cell cycle arrest and apoptosis in tumor cells. Goniothalamin acts as a larvicide against Culex quinquefasciatus larvae and as a cytotoxin against brine shrimp larvae. Goniothalamin functions as an antibacterial agent against Gram-positive and Gram-negative bacteria, and also acts as an antifungal agent against pathogens including Candida albicans, Trichophyton rubrum and Trichophyton mentagrophytes. Goniothalamin is applicable to research related to breast cancer, lymphatic filariasis, bacterial infections and fungal infections .

Filiformin (-)-Filiformin	Structural Classification Terpenoids Marine algae Sesquiterpenes Marine natural products Source Classification	Bacterial
Filiformin ((-)-Filiformin) is a sesquiterpene compound that can be isolated from Laurencia filiformis forma heteroclada. Filiformin exhibits certain cytotoxicity against P388 and BSC-1 cells. Filiformin has antimicrobial activity against Bacillus subtilis, Trichophyton mentagrophytes and Candida albicans. In addition, Filiformin can inhibit oxygen uptake in isolated rat liver mitochondria at a concentration of 150 μM .

Nyasol (-)-Nyasol; (Z)-Hinokiresinol; cis-Hinokiresinol	Phenols Polyphenols Hypoxis angustifolia Lam. Plants Source Classification Asparagaceae Juss.	NO Synthase Bacterial Fungal Parasite Leukotriene Receptor
Nyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells .

Anisocoumarin H	Adenocarpus cincinnatus (Ball) Maire Coumarins Phenylpropanoids Plants Compositae Source Classification	Fungal
Anisocoumarin H is a coumarin that exhibits antifungal activity. Anisocoumarin H shows the activities against Microsporum gypseum, Trichophyton rubrum and Trichophyton mentagrophytes with MICs of 62.5 µg/mL .

Phellinsin	Natural Products Microorganisms Source Classification	Fungal
Phellinsin selectively inhibits the activity of the chitin synthase I and II with IC₅₀s (μg/mL) of 76 and 28, respectively. Phellinsin has the antifungal activity on Colletotrichum lagenarium, Pyricularia oryzae, Aspergillus fumigatus and Trichophyton mentagrophytes and so on (MIC is 12.5-50 μg/mL) .

Akrobomycin	Microorganisms Antibiotics Other Antibiotics Source Classification	Fungal
Akrobomycin is an anthracycline antibiotic. Akrobomycin shows antimicrobial and antitumor activities .

2-Deethoxy-2-hydroxyphantomolin	Structural Classification Other Monoterpenes Terpenoids Plants Boraginaceae Source Classification	Bacterial Fungal
2-Deethoxy-2-hydroxyphantomolin, Germacranolide, is an Antifungal and Antibacterial agent. 2-Deethoxy-2-hydroxyphantomolin can be isolated from Elephantopus tomentosus Linn and E. mollis. 2-Deethoxy-2-hydroxyphantomolin is moderately active against Candida albicans (14 mm clearing zone) and slightly active against Escherichia coli (12 mm), Pseudomonas aeruginosa (12 mm), Bacillus subtilis (14 mm), and Trichophyton mentagrophytes (13 mm) .

Gladiolic acid	Natural Products Microorganisms Source Classification	Fungal
Gladiolic acid has the antifungal activity of Absidia glauca Hagem, garlic spores, Byssochlamys fulva, Trichophyton mentagrophytes, Corpuscular falciparum .

Drimenal	Structural Classification Natural Products Bazzania trilobata (L.) Gray Lepidoziaceae Plants Source Classification	Fungal
Drimenal is a pimarane-type natural sesquiterpene with antifungal activity. Drimenal inhibits the growth of yeasts and dermatophytes. Drimenal can be used for the development of pesticide candidates and in research related to fungal infections .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Trichophyton mentagrophytes

Inhibitors & Agonists

NaturalProducts

Natural
Products