2. Anti-infection
  3. Bacterial Fungal
  4. Cladobotric acid E

Cladobotric acid E is a potent antimicrobial agent that can be found in mycoparasitic fungi and a New Zealand Cladobotryum species. Cladobotric acid E inhibits growth of Candida auris, multiple Aspergillus species, Candida albicans, Trichophyton mentagrophytes, and Cladosporium resinae. Cladobotric acid E can be used for the research of aspergillosis, candidiasis, leukemia, bacterial infection, fungal infection.

For research use only. We do not sell to patients.

Cladobotric acid E

Cladobotric acid E Chemical Structure

CAS No. : 876152-18-0

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Cladobotric acid E Related Antibodies

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Description

Cladobotric acid E is a potent antimicrobial agent that can be found in mycoparasitic fungi and a New Zealand Cladobotryum species. Cladobotric acid E inhibits growth of Candida auris, multiple Aspergillus species, Candida albicans, Trichophyton mentagrophytes, and Cladosporium resinae. Cladobotric acid E can be used for the research of aspergillosis, candidiasis, leukemia, bacterial infection, fungal infection[1][2][3].

In Vitro

Cladobotric acid E (2-64 µg/mL) potently inhibits growth of azole-sensitive and azole-resistant Candida auris strains with MICs of 2-4 µg/mL and shows moderate to weak activity against Aspergillus species with MICs of 8-64 µg/mL[1].
Cladobotric acid E (0.1-10 µg/disc; 48 h) inhibits growth of Aspergillus fumigatus IFM 61493, Aspergillus lentulus IFM 62073, Aspergillus felis IFM 62093, and Aspergillus udagawae IFM 62100 in a paper disc assay, with the largest inhibition zone (17 mm) observed against A. udagawae at 3 µg/disc[2].
Cladobotric acid E (1-256 µg/mL; 48-72 h) inhibits growth of Aspergillus fumigatus IFM 61493 with an MIC of 16 µg/mL, and Aspergillus lentulus IFM 62073, Aspergillus felis IFM 62093, and Aspergillus udagawae IFM 62100 each with an MIC of 32 µg/mL in a microdilution assay[2].
Cladobotric acid E potently inhibits the growth of murine P388 leukemia cells with an IC50 of 1.41 μM[3].
Cladobotric acid E (100 μg/disc) inhibits the growth of Bacillus subtilis with a 4 mm inhibition zone at a concentration of 100 μg/disc[3].
Cladobotric acid E (100 μg/disc) inhibits the growth of Candida albicans with a 5 mm inhibition zone at a concentration of 100 μg/disc[3].
Cladobotric acid E (100 μg/disc) inhibits the growth of Trichophyton mentagrophytes with a 2 mm inhibition zone at a concentration of 100 μg/disc[3].
Cladobotric acid E (100 μg/disc) inhibits the growth of Cladosporium resinae with a 1 mm inhibition zone at a concentration of 100 μg/disc[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cladobotric acid E Related Antibodies
Molecular Weight

456.58

Formula

C27H36O6
CAS No.
SMILES

C[C@]1([C@@]([C@@H](CC)C)(O1)[H])[C@@]2(O)[C@@H](/C=C/C=C/C=C/C(O)=O)[C@]3([C@](C=C2C)(CC(C(OC)=O)=CC3)[H])[H]
Structure Classification
Initial Source

Cladobotryum sp.
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Cladobotric acid E Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cladobotric acid E876152-18-0BacterialFungalCandida albicansCandida aurisaspergillosisleukemia cellsBacillus subtilisCladosporium resinaecandidiasisTrichophyton mentagrophytesmurine P388 leukemia cellsAspergillus speciesInhibitorinhibitorinhibit

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