876152-18-0
Chemical Structure
Cladobotric acid E
- CAS No.: 876152-18-0
- Formula:C27H36O6
- Molecular Weight:456.58
IUPAC Name: (2E,4E,6E)-7-((1S,2R,4aR,8aR)-2-((2S,3R)-3-((R)-sec-butyl)-2-methyloxiran-2-yl)-2-hydroxy-6-(methoxycarbonyl)-3-methyl-1,2,4a,5,8,8a-hexahydronaphthalen-1-yl)hepta-2,4,6-trienoic acid
InChIKey: MKFMCRKTWMJGHB-HIIGJWGWSA-N
SMILES: C[C@]1([C@@]([C@@H](CC)C)(O1)[H])[C@@]2(O)[C@@H](/C=C/C=C/C=C/C(O)=O)[C@]3([C@](C=C2C)(CC(C(OC)=O)=CC3)[H])[H]
Biological Activity: Cladobotric acid E is a potent antimicrobial agent that can be found in mycoparasitic fungi and a New Zealand Cladobotryum species. Cladobotric acid E inhibits growth of Candida auris, multiple Aspergillus species, Candida albicans, Trichophyton mentagrophytes, and Cladosporium resinae. Cladobotric acid E can be used for the research of aspergillosis, candidiasis, leukemia, bacterial infection, fungal infection[1][2][3].
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Cladobotric acid E | Cladobotric acid E is a potent antimicrobial agent that can be found in mycoparasitic fungi and a New Zealand Cladobotryum species. Cladobotric acid E inhibits growth of Candida auris, multiple Aspergillus species, Candida albicans, Trichophyton mentagrophytes, and Cladosporium resinae. Cladobotric acid E can be used for the research of aspergillosis, candidiasis, leukemia, bacterial infection, fungal infection. | |||||||||||||||||||||
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- [1]. Wang L, et al. Natural Polyketides Act as Promising Antifungal Agents. Biomolecules. 2023 Oct 24;13(11):1572. [Content Brief]
- [2]. Watanabe Y, et al. Hakuhybotric acid, a new antifungal polyketide produced by a mycoparasitic fungus Hypomyces pseudocorticiicola FKI-9008. J Gen Appl Microbiol. 2022 Nov 22;68(4):200-206. [Content Brief]
- [3]. Mitova MI, et al. Cladobotric acids A-F: new cytotoxic polyketides from a New Zealand Cladobotryum sp. J Org Chem. 2006 Jan 20;71(2):492-7. [Content Brief]
Keywords
