61 Results for "

Tripterygium

" in MedChemExpress (MCE) Product Catalog:
Products (61)

61 Results for "Tripterygium" in MCE Product Catalog:

74
74 Publications Verification
Cat. No.: HY-32735
CAS No.: 38748-32-2
Synonyms: PG490
Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .
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6
6 Cited Publications
Cat. No.: HY-N0587
CAS No.: 107316-88-1
Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation [1][2].
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4
4 Cited Publications
Cat. No.: HY-32736
CAS No.: 38647-11-9
Synonyms: NSC 165677; PG 492
Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .
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Cat. No.: HY-N0899
CAS No.: 11088-09-8
Wilforine is an orally active JAK-STAT pathway inhibitor with immunomodulatory effects and the ability to inhibit osteoclast fusion. Wilforine disrupts lipid raft integrity, reprograms cholesterol and glycosphingolipid metabolic pathways, regulates NF-κB and the complement system, and modulates the expression of various interleukins. Wilforine also inhibits the Wnt11/β-catenin signaling pathway and suppresses the proliferation of fibroblast-like synoviocytes. Wilforine can serve as a quality and pharmacokinetic marker for Tripterygium glycoside tablets, and can be applied to research on related diseases such as rheumatoid arthritis, inflammatory osteolysis, and SAPHO syndrome .
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Cat. No.: HY-N0475
CAS No.: 74285-86-2
Synonyms: Hypolide; (+)-Triptophenolide
Triptophenolide (Hypolide) is a colorless crystal isolated from the ethyl acetate extract of Tripterygium wilfordii. Triptophenolide is an orally active pan‑antagonist of the androgen receptor (AR) with an IC50 of 467 nM against human wild‑type AR. Triptophenolide reduces AR expression, inhibits AR nuclear translocation, downregulates prostate‑specific antigen mRNA levels, and suppresses the growth of AR‑positive prostate cancer cells. Triptophenolide shows anti-tumor effects against breast cancer by inhibiting cell proliferation and migration, inducing G1-phase arrest and apoptosis, repressing xenograft tumor growth. Triptophenolide inhibits pyroptosis, alleviates tissue inflammation, and ameliorates synovial injury. Triptophenolide can be used for the study of prostate cancer, rheumatoid arthritis and breast cancer .
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Cat. No.: HY-N0476
CAS No.: 84104-71-2
Synonyms: Regelide; Abruslactone A
Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects .
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Cat. No.: HY-N1999
CAS No.: 37239-51-3
Wilfordine is an alkaloid that isolated from the roots of Tripterygium wilfordii .
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Cat. No.: HY-32735S
Synonyms: PG490-d3
Triptolide-d3 is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .
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Cat. No.: HY-107101
CAS No.: 583028-68-6
Purity:  99.67%
Synonyms: PG 701; LLDT-8; 5α-Hydroxytriptolide
(5R)-5-Hydroxytriptolide is an extracted compound from Tripterygium, and shows lower cell cytotoxicity and higher immunosuppressive activity. (5R)-5-Hydroxytriptolide can be used for study of rheumatoid arthritis .
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Cat. No.: HY-32735R
CAS No.: 38748-32-2
Synonyms: PG490 (Standard)
Triptolide (Standard) is the analytical standard of Triptolide. This product is intended for research and analytical applications. Triptolide is a diterpenoid triepoxide extracted from the root of Tripterygium wilfordii with immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is a NF-κB activation inhibitor .
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Cat. No.: HY-N1072
CAS No.: 37239-47-7
Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system .
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Cat. No.: HY-N0587R
CAS No.: 107316-88-1
Demethylzeylasteral (Standard) is the analytical standard of Demethylzeylasteral. This product is intended for research and analytical applications. Demethylzeylasteral is an orally active triterpenoid compound isolated from Tripterygium wilfordii, which has functions such as anti-inflammatory, anti-tumor, anti fertility, estrogen metabolism regulation, immune suppression, and immune system regulation .
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Cat. No.: HY-N10408
CAS No.: 132368-08-2
Target:  

Apoptosis Autophagy

Research Areas:  

Neurological Disease Cancer

Tripchlorolide is a neuroprotective agent that can be found in Tripterygium wilfordii. Tripchlorolide prevents tumor growth by inducing apoptosis and autophagy. Tripchlorolide improves cognitive deficits in Alzheimer's disease .
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Cat. No.: HY-32736R
CAS No.: 38647-11-9
Synonyms: NSC 165677 (Standard); PG 492 (Standard)
Triptonide (Standard) is the analytical standard of Triptonide. This product is intended for research and analytical applications. Triptonide (NSC 165677) is a natural product identified in Tripterygium wilfordii Hook F.. Triptonide is a Wnt signaling inhibitor with an IC50 of appropriately 0.3 nM. Triptonide has immunosuppression, anti-inflammatory, anti-fertility, neuroprotective and anti-lymphoma effects .
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Cat. No.: HY-N17695
CAS No.: 53990-48-0
(-)-Celallocinnine (MOL003209) is an orally active ingredient of Tripterygium wilfordii. (-)-Celallocinnine can be used for the research of diabetic nephropathy .
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Cat. No.: HY-N11601
CAS No.: 138570-50-0
Tripterygone is a chemical component that can be extracted from Tripterygium wilfordii. Tripterygone is a pentacyclic triterpenoid compound. Tripterygone is a potential anti-inflammatory agent .
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Cat. No.: HY-N11784
CAS No.: 99694-86-7
Triptolidenol, a traditional Chinese medicine, is an epoxy diterpene lactone that can be isolated from Tripterygium wilfordii. Triptolidenol has anti-inflammatory and anticancer activities. Triptolidenol significantly inhibits tumor cell proliferation and migration, arrests cell cycle arrest at S phase and induces apoptosis by activating the cytochrome c/caspase cascade signaling pathway. Triptolidenol disrupts NF-κB/COX-2 pathway by inhibiting IKKβ at ATP-binding sites. Triptolidenol can be used for chronic nephritis and kidney cancer like clear cell renal cell carcinoma (ccRCC) research .
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Cat. No.: HY-N1118
CAS No.: 84108-17-8
Synonyms: Abrusgenic acid; Maytenfolic acid
Triptotriterpenic acid A is a natural product from Tripterygium wilfordii .
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Cat. No.: HY-N6912
CAS No.: 114542-54-0
Regelidine is a natural product isolated from the stems of Tripterygium regelii .
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Cat. No.: HY-N10406
CAS No.: 99694-87-8
Triptonoterpene is a natural product that can be isolated from the roots of Tripterygium wilfordii Hook. f. .
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