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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
VH 101, thiol
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "VH 101, thiol" in MCE Product Catalog:
Cat. No.: HY-47851
CAS No.: 2358775-81-0
Target:
Research Areas:
VH 101, thiol (compound 20) is a VHL ligand for the synthesis of PROTACs .
Cat. No.: HY-168448
CAS No.: 3104449-57-9
Target:
Research Areas:
dBAZ2 is a first-in-class BAZ2A and BAZ2B PROTAC degrader with DC50 values of 180 nM and 250 nM for BAZ2A and BAZ2B, respectively. (Blue: E3 ligase ligand (VH 101, thiol (HY-47851); Black: linker (HY-168450); pink: target protein ligand (HY-168449)) .
Cat. No.: HY-168451
Research Areas:
trans-VH 101-Thiol-C-cyclohexane-p-C-OTs is the conjugate of an ligand for E3 ligase ligand and a linker, that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448) .
Cat. No.: HY-181737
Research Areas:
E3 Ligase Ligand-linker Conjugate 225 is an E3 ligase ligand-linker conjugate used for the synthesis of PROTACs; it consists of the PEG-based linker Bis-Tos-PEG3 (HY-W013731) and the VHL-type E3 ubiquitin ligase ligand VH 101 thiol (HY-47851). E3 Ligase Ligand-linker Conjugate 225 can be further coupled with a target protein ligand—such as MT-4 (HY-128595)—to synthesize the PROTAC TG2 Degrader-3 (HY-181732) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
