VH 101, thiol
Based on 1 Customer Validation
VH 101, thiol (compound 20) is a VHL ligand for the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 98.66%
- CAS No.: 2358775-81-0
- Formula: C25H31FN4O4S2
- Molecular Weight:534.67
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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VHL |
Chemical Information
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CAS No. 2358775-81-0
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Appearance Solid
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Molecular Weight 534.67
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Formula C25H31FN4O4S2
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SMILES
O=C(C1(CC1)F)N[C@@H](C(C)(S)C)C(N2[C@@H](C[C@H](C2)O)C(NCC3=CC=C(C4=C(N=CS4)C)C=C3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (187.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8703 mL | 9.3516 mL | 18.7031 mL | 46.7578 mL |
| 5 mM | 0.3741 mL | 1.8703 mL | 3.7406 mL | 9.3516 mL | |
| 10 mM | 0.1870 mL | 0.9352 mL | 1.8703 mL | 4.6758 mL | |
| 15 mM | 0.1247 mL | 0.6234 mL | 1.2469 mL | 3.1172 mL | |
| 20 mM | 0.0935 mL | 0.4676 mL | 0.9352 mL | 2.3379 mL | |
| 25 mM | 0.0748 mL | 0.3741 mL | 0.7481 mL | 1.8703 mL | |
| 30 mM | 0.0623 mL | 0.3117 mL | 0.6234 mL | 1.5586 mL | |
| 40 mM | 0.0468 mL | 0.2338 mL | 0.4676 mL | 1.1689 mL | |
| 50 mM | 0.0374 mL | 0.1870 mL | 0.3741 mL | 0.9352 mL | |
| 60 mM | 0.0312 mL | 0.1559 mL | 0.3117 mL | 0.7793 mL | |
| 80 mM | 0.0234 mL | 0.1169 mL | 0.2338 mL | 0.5845 mL | |
| 100 mM | 0.0187 mL | 0.0935 mL | 0.1870 mL | 0.4676 mL |
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