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Cat. No.: HY-168451

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trans-VH 101-Thiol-C-cyclohexane-p-C-OTs

trans-VH 101-Thiol-C-cyclohexane-p-C-OTs is the conjugate of an ligand for E3 ligase ligand and a linker, that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448).

For research use only. We do not sell to patients.

Formula: C₄₀H₅₁FN₄O₇S₃
Molecular Weight:815.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

trans-VH 101-Thiol-C-cyclohexane-p-C-OTs Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

trans-VH 101-Thiol-C-cyclohexane-p-C-OTs is the conjugate of an ligand for E3 ligase ligand and a linker, that can be used for synthesis of PROTAC degrader dBAZ2 (HY-168448)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 815.05
Formula C₄₀H₅₁FN₄O₇S₃
SMILES

CC1=C(SC=N1)C2=CC=C(C=C2)CNC([C@@H]3C[C@H](CN3C([C@H](C(C)(SC[C@H]4CC[C@@H](CC4)COS(C5=CC=C(C)C=C5)(=O)=O)C)NC(C6(CC6)F)=O)=O)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Palaferri L, et al. Discovery of First-in-Class BAZ2A/B and BAZ2B-Selective Degraders[J]. ACS Medicinal Chemistry Letters, 2025.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

trans-VH 101-Thiol-C-cyclohexane-p-C-OTs

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trans-VH 101-Thiol-C-cyclohexane-p-C-OTs

All E3 Ligase Ligand-Linker Conjugates Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

trans-VH 101-Thiol-C-cyclohexane-p-C-OTs Related Classifications

HY-168451 Related Classifications

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