3 Results for "

Vinblastine derivatives

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Vinblastine derivatives" in MCE Product Catalog:

Cat. No.: HY-16514
CAS No.: 53643-48-4
Research Areas:  

Cancer

Vindesine is a derivative of Vinblastine (HY-13780). Vindesine binds to and stabilizes tubulin . Vindesine inhibits mitosis in cancer cells and prevents the invasion of normal tissues by malignant cells. Vindesine can be used in cancer research .
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Cat. No.: HY-P10589
CAS No.: 89085-54-1
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

Phomopsinamine A is a derivative of Phomopsin A (HY-N6793). Phomopsinamine A is an inhibitor for tubulin polymerization with IC50 of 0.53 μM. Phomopsinamine A inhibits the binding of Vinblastine (HY-13780) to tubulin (IC50 =0.56 μM), promotes the the binding of Colchicine (HY-16569) to tubulin (IC50 =0.32 μM) .
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Cat. No.: HY-157876
Target:  

P-glycoprotein BCRP

Research Areas:  

Cancer

Anticancer agent 191 (Compound 2) is a derivative of probenecid (HY-B0545). As a cancer cell efflux inhibitor, Anticancer agent 191 is designed to inhibit P-glycoprotein (P-gp), breast cancer resistance protein (BCRP), and/or multiple multidrug resistance proteins (MRPs). Anticancer agent 191 increases the accumulation of vinblastine in cancer cells, which is used for cancer research .
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