53643-48-4
Chemical Structure
Vindesine
- CAS No.: 53643-48-4
- Formula:C43H55N5O7
- Molecular Weight:753.93
IUPAC Name: methyl (3S,5S,7S,9S)-9-((3aR,3a1R,4R,5S,5aR,10bR)-5-carbamoyl-3a-ethyl-4,5-dihydroxy-8-methoxy-6-methyl-3a,3a1,4,5,5a,6,11,12-octahydro-1H-indolizino[8,1-cd]carbazol-9-yl)-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methano[1]azacycloundecino[5,4-b]indole-9-carboxylate
InChIKey: HHJUWIANJFBDHT-KOTLKJBCSA-N
SMILES: CN([C@]1([H])[C@@]23[C@]4([H])[C@](C=CCN4CC3)(CC)[C@@H](O)[C@]1(O)C(N)=O)C(C2=C5)=CC(OC)=C5[C@](C[C@]6([H])C[N@]7C[C@@](CC)(O)C6)(C(OC)=O)C8=C(CC7)C9=CC=CC=C9N8
Biological Activity: Vindesine is a derivative of Vinblastine (HY-13780). Vindesine binds to and stabilizes tubulin. Vindesine inhibits mitosis in cancer cells and prevents the invasion of normal tissues by malignant cells. Vindesine can be used in cancer research[1].
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Vindesine | Vindesine is a derivative of Vinblastine (HY-13780). Vindesine binds to and stabilizes tubulin. Vindesine inhibits mitosis in cancer cells and prevents the invasion of normal tissues by malignant cells. Vindesine can be used in cancer research. | |||||||||||||||||||||
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Keywords
