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Zingiber officinale

" in MedChemExpress (MCE) Product Catalog:

標的別:	5-HT Receptor (1) AMPK (2) Apoptosis (2) Autophagy (2) Bacterial (1) COX (3) Drug Derivative (3) Drug Isomer (1) Environmental Pollutants (1) ERK (1) Fungal (2) HIV (1) IKK (1) Interleukin Related (5) JNK (1) NF-κB (4) NO Synthase (3) Parasite (2) Reactive Oxygen Species (ROS) (1) Reference Standards (4) TNF Receptor (1)
研究分野別:	Cancer (10) Infection (5) Inflammation/Immunology (9) Metabolic Disease (3) Neurological Disease (3)

阻害剤およびアゴニスト

天然物

製品番号	製品名	Target	研究分野	構造式

HY-14615

[6]-Gingerol Maximum Cited Publications 13 Publications Verification (S)-(+)-[6]Gingerol	AMPK Apoptosis	Cancer
[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-14616

Shogaol 10+ Cited Publications [6]-Shogaol; 6-Shogaol	Autophagy	Cancer
Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-14621

Zingerone 5+ Cited Publications Vanillylacetone; Gingerone	Environmental Pollutants NF-κB	Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells . Zingerone can cross the blood-brain barrier (BBB) .

HY-14615R

[6]-Gingerol (Standard) 1 Publications Verification (S)-(+)-[6]Gingerol (Standard)	Reference Standards AMPK Apoptosis	Cancer
-Gingerol (Standard) is the analytical standard of -Gingerol. This product is intended for research and analytical applications. -Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-N2434

[10]-Shogaol 5 Publications Verification	COX Interleukin Related NF-κB Parasite	Infection Inflammation/Immunology Cancer
[10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC₅₀ value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis .

HY-133865

Diacetoxy-6-gingerdiol 1 Publications Verification	Interleukin Related	Metabolic Disease Inflammation/Immunology
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .

HY-W1000105

Geranial (E)-3,7-Dimethylocta-2,6-dienal	TNF Receptor Interleukin Related ERK JNK IKK COX NO Synthase Reactive Oxygen Species (ROS)	Inflammation/Immunology
Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger (Zingiber officinale). Geranial inhibits LPS-induced phosphorylation of ERK1/2, JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β, TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2. Geranial increases ROS. It can be used in the research of inflammatory diseases .

HY-14616R

Shogaol (Standard) 1 Publications Verification [6]-Shogaol (Standard); 6-Shogaol (Standard)	Reference Standards Autophagy	Cancer
Shogaol (Standard) is the analytical standard of Shogaol. This product is intended for research and analytical applications. Shogaol ( -Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

HY-W711045

Deoxygeraniol	Drug Derivative	Others
Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings.

HY-N16519

[6]-Gingerdiol	Fungal	Infection
[6]-Gingerdiol is an antifungal agent. [6]-Gingerdiol can be isolated from Zingiber officinale. [6]-Gingerdiol shows antifungal activity against M. gypseum with a MLC value of 422 μg/mL.

HY-N16553

(3R,5S)-[4]-Gingerdiol	Others	Inflammation/Immunology
(3R,5S)-[4]-Gingerdiol (compound 32) is a gingerdiol from Zingiber officinale. (3R,5S)-[4]-Gingerdiol can be used for anti-inflammatory research .

HY-109088

Enexasogaol trans-6-Shogaol; (E)-[6]-Shogaol	Drug Derivative	Cancer
Enexasogaol (trans-6-Shogaol; (E)-[6]-Shogaol) is the derivative of Shogaol (HY-14616) found in Ginger (Zingiber officinale Rosc). Enexasogaol can be used for the research of cancer .

HY-N18375

7-Gingerdiol	Drug Derivative	Others
7-Gingerdiol is a ginger phenol found in Zingiber officinale rhizomes .

HY-N9092

Geranyl ferulate (E)-geranylferulic acid	NO Synthase	Infection Inflammation/Immunology
Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO) .

HY-N16501

(3S,5S)-[4]-Gingerdiol	Others	Others
(3S,5S)-[4]-Gingerdiol is a phenylalkanoid can be found in Zingiber officinale .

HY-N10792

Methyl diacetoxy-6-gingerdiol	Others	Others
Methyl diacetoxy-6-gingerdiol is a nature product that could be isolated form the rhizomes of Zingiber officinale .

HY-N13114

8-Gingerdione	Others	Others
8-Gingerdione can be isolated from ginger (Zingiber officinale). 8-Gingerdione has no significant inhibitory effect on the production of inflammatory factors NO, TNF-α, and IL-6.

HY-N17725

(3S,5S)-5'-Methoxyoctahydrocurcumin	Others	Others
(3S,5S)-5'-Methoxyoctahydrocurcumin (Compound 13) is a diarylheptanoid that can be found in the dried rhizoma of Zingiber officinale Roscoe .

HY-N2434A

(E)-[10]-Shogaol	5-HT Receptor	Neurological Disease
(E)-[10]-Shogaol is a 5-HT_1A receptor partial agonist found in Zingiber officinale, with a K_i of 5.84 μM. (E)-[10]-Shogaol may be used in research on anxiety and depression .

HY-N9891

12-Dehydrogingerdione 12-DHGD	NO Synthase Interleukin Related	Inflammation/Immunology
12-Dehydrogingerdione is an inhibitor of NO Synthase. 12-Dehydrogingerdione signi?cantly inhibits LPS-stimulated production of NO, IL-6 and PGE2 in Raw 264.7 cells .

HY-14621R

Zingerone (Standard) Vanillylacetone (Standard); Gingerone (Standard)	Reference Standards NF-κB	Metabolic Disease Inflammation/Immunology Cancer
Zingerone (Standard) is the analytical standard of Zingerone. This product is intended for research and analytical applications. Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells .

HY-134635R

Dehydrozingerone (Standard)	Bacterial Fungal HIV	Infection Neurological Disease Cancer
Dehydrozingerone (Standard) is the analytical standard of Dehydrozingerone. This product is intended for research and analytical applications. Dehydrozingerone (Compound 10), a structural half analogue of Curcumin (HY-N0005), is a phenolic compound with antibacterial, anticancer, antioxidant, anti-Alzheimer’s and antifungal activity, which is isolated from ginger (Zingiber officinale) rhizomes. Dehydrozingerone shows moderate inhibitory activities on the secretion of HBsAg in HepG 2 cells with an IC50 value of 0.50 mM .

HY-120912A

(E/Z)-Gingerenone A	Drug Isomer	Others
(E/Z)-Gingerenone A (Compound 42) is a diarylheptanoid compound. (E/Z)-Gingerenone A is isolated from the rhizomes of Zingiber officinale Rosc .

HY-N2434R

[10]-Shogaol (Standard)	Reference Standards COX Interleukin Related NF-κB Parasite	Infection Inflammation/Immunology Cancer
-Shogaol (Standard) is the analytical standard of -Shogaol (HY-N2434). This product is intended for research and analytical applications. [10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC₅₀ value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis .

HY-N15733

5-Methoxy-[8]-gingerol	Others	Others
5-Methoxy-[8]-gingerol is a compound that can be isolated from ginger (Zingiber officinale) .

HY-N9243

5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate	Others	Others
5-Hydroxy-1,7-bis(4-hydroxyphenyl)heptan-3-yl acetate is a Phenols product that can be isolated from the rhizomes of Zingiber officinale .

[6]-Gingerol Maximum Cited Publications 13 Publications Verification (S)-(+)-[6]Gingerol	Zingiber officinale Roscoe Structural Classification Monophenols Classification of Application Fields Phenols Plants Disease Research Fields Source Classification Zingiberaceae Cancer	AMPK Apoptosis
[6]-Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

Shogaol 10+ Cited Publications [6]-Shogaol; 6-Shogaol	Zingiber officinale Roscoe Monophenols Classification of Application Fields Phenols Plants Disease Research Fields Source Classification Zingiberaceae Cancer	Autophagy
Shogaol ([6]-Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

Zingerone 5+ Cited Publications Vanillylacetone; Gingerone	Zingiber officinale Roscoe Structural Classification Monophenols Classification of Application Fields Ketones, Aldehydes, Acids Phenols Metabolic Disease Plants Inflammation/Immunology Disease Research Fields Source Classification Zingiberaceae	Environmental Pollutants NF-κB
Zingerone (Vanillylacetone) is a nontoxic methoxyphenol isolated from Zingiber officinale, with potent anti-inflammatory, antidiabetic, antilipolytic, antidiarrhoeic, antispasmodic and anti-tumor properties . Zingerone alleviates oxidative stress and inflammation, down-regulates NF-κB mediated signaling pathways . Zingerone acts as an anti-mitotic agent, and inhibits the growth of neuroblastoma cells . Zingerone can cross the blood-brain barrier (BBB) .

[6]-Gingerol (Standard) 1 Publications Verification (S)-(+)-[6]Gingerol (Standard)	Zingiber officinale Roscoe Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Reference Standards AMPK Apoptosis
-Gingerol (Standard) is the analytical standard of -Gingerol. This product is intended for research and analytical applications. -Gingerol is an active compound isolated from Ginger (Zingiber officinale), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

[10]-Shogaol 5 Publications Verification	Zingiber officinale Roscoe Structural Classification Monophenols Classification of Application Fields Phenols Plants Disease Research Fields Source Classification Zingiberaceae Cancer	COX Interleukin Related NF-κB Parasite
[10]-Shogaol is an orally active antioxidant. [10]-Shogaol can be extracted from ginger (Zingiber officinale). [10]-Shogaol1 inhibits COX-2 with an IC₅₀ value of 7.5 μM. [10]-Shogaol inhibits the production of proinflammatory cytokines (IL-1β, IL-6). [10]-Shogaol inhibits NF-κB phosphorylation. [10]-Shogaol has anti-inflammatory effects. [10]-Shogaol has anticancer effects against Docetaxel (HY-B0011)-resistant prostate cancer. [10]-Shogaol exhibits larvicidal activity against L5 larvae of Angiostrongylus cantonensis .

Diacetoxy-6-gingerdiol 1 Publications Verification	Zingiber officinale Roscoe Monophenols Classification of Application Fields Other Diseases Phenols Plants Disease Research Fields Source Classification Zingiberaceae	Interleukin Related
Diacetoxy-6-gingerdiol is a gingerol isolated with anti-inflammatory and antioxidant effects, which is found in the dichloromethane extract of rhizomes of ginger (Zingiber officinale Roscoe). Diacetoxy-6-gingerdiol protects the extracellular matrix of nucleus pulposus cells and ameliorates intervertebral disc degeneration by inhibiting the IL-1β-mediated NLRP3 pathway .

Shogaol (Standard) 1 Publications Verification [6]-Shogaol (Standard); 6-Shogaol (Standard)	Zingiber officinale Roscoe Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Reference Standards Autophagy
Shogaol (Standard) is the analytical standard of Shogaol. This product is intended for research and analytical applications. Shogaol ( -Shogaol), an active compound isolated from Ginger (Zingiber officinale Rosc), exhibits a variety of biological activities including anticancer, anti-inflammation, and anti-oxidation.

Deoxygeraniol	Structural Classification Other Monoterpenes Terpenoids Magnoliaceae Oyama sieboldii (K. Koch) N. H. Xia & C. Y. Wu Plants Source Classification	Drug Derivative
Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings.

[6]-Gingerdiol	Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Fungal
[6]-Gingerdiol is an antifungal agent. [6]-Gingerdiol can be isolated from Zingiber officinale. [6]-Gingerdiol shows antifungal activity against M. gypseum with a MLC value of 422 μg/mL.

(3R,5S)-[4]-Gingerdiol	Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Others
(3R,5S)-[4]-Gingerdiol (compound 32) is a gingerdiol from Zingiber officinale. (3R,5S)-[4]-Gingerdiol can be used for anti-inflammatory research .

Enexasogaol trans-6-Shogaol; (E)-[6]-Shogaol	Zingiber officinale Roscoe Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Drug Derivative
Enexasogaol (trans-6-Shogaol; (E)-[6]-Shogaol) is the derivative of Shogaol (HY-14616) found in Ginger (Zingiber officinale Rosc). Enexasogaol can be used for the research of cancer .

7-Gingerdiol	Zingiber officinale Roscoe Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Drug Derivative
7-Gingerdiol is a ginger phenol found in Zingiber officinale rhizomes .

Geranyl ferulate (E)-geranylferulic acid	Zingiber officinale Roscoe Monophenols Classification of Application Fields Simple Phenylpropanols Phenols Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology Source Classification Zingiberaceae	NO Synthase
Geranyl ferulate ((E)-geranylferulic acid), isolated from Zingiber officinale, exhibits inhibitory effect on the production of nitric oxide (NO) .

(3S,5S)-[4]-Gingerdiol	Structural Classification Monophenols Phenols Plants Source Classification Zingiberaceae	Others
(3S,5S)-[4]-Gingerdiol is a phenylalkanoid can be found in Zingiber officinale .

Methyl diacetoxy-6-gingerdiol	Phenols Plants Source Classification Zingiberaceae	Others
Methyl diacetoxy-6-gingerdiol is a nature product that could be isolated form the rhizomes of Zingiber officinale .

8-Gingerdione	Zingiber officinale Roscoe Monophenols Phenols Plants Source Classification Zingiberaceae	Others
8-Gingerdione can be isolated from ginger (Zingiber officinale). 8-Gingerdione has no significant inhibitory effect on the production of inflammatory factors NO, TNF-α, and IL-6.

(3S,5S)-5'-Methoxyoctahydrocurcumin	Zingiber officinale Roscoe Structural Classification Phenols Plants Source Classification Zingiberaceae	Others
(3S,5S)-5'-Methoxyoctahydrocurcumin (Compound 13) is a diarylheptanoid that can be found in the dried rhizoma of Zingiber officinale Roscoe .

(E)-[10]-Shogaol	Zingiber officinale Roscoe Structural Classification Monophenols Animals Phenols Plants Source Classification Zingiberaceae	5-HT Receptor
(E)-[10]-Shogaol is a 5-HT_1A receptor partial agonist found in Zingiber officinale, with a K_i of 5.84 μM. (E)-[10]-Shogaol may be used in research on anxiety and depression .

12-Dehydrogingerdione 12-DHGD	Zingiber officinale Roscoe Monophenols Phenols Plants Source Classification Zingiberaceae	NO Synthase Interleukin Related
12-Dehydrogingerdione is an inhibitor of NO Synthase. 12-Dehydrogingerdione signi?cantly inhibits LPS-stimulated production of NO, IL-6 and PGE2 in Raw 264.7 cells .

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