141-27-5
141-27-5
Chemical Structure
Geranial
Synonym(s): (E)-3,7-Dimethylocta-2,6-dienal
- CAS No.: 141-27-5
- Formula:C10H16O
- Molecular Weight:152.23
InChIKey: WTEVQBCEXWBHNA-JXMROGBWSA-N
SMILES: C/C(C)=C\CC/C(C)=C/C=O
Biological Activity: Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger (Zingiber officinale). Geranial inhibits LPS-induced phosphorylation of ERK1/2, JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β, TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2. Geranial increases ROS. It can be used in the research of inflammatory diseases[1][2].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Geranial | 99.51% | Geranial is an aromatic compound. It can be isolated from the fruits of Litsea cubeba Lour and the rhizomes of ginger (Zingiber officinale). Geranial inhibits LPS-induced phosphorylation of ERK1/2, JNK1/3 and IκB in macrophages. It suppresses the secretion of IL-1β, TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2. Geranial increases ROS. It can be used in the research of inflammatory diseases. | ||||||||||||||||||||
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Geranylamine | Geranylamine is an acyclic monoterpene amine that serves as a drug intermediate for the synthesis of a series of TRP channel modulators and antibacterial agents. | |||||||||||||||||||||
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Geraniol | 98.62% | Geraniol is an olefin terpene with oral activity. Geraniol inhibits cell proliferation and promotes apoptosis. Geraniol has antibacterial, antifungal, antioxidant, anti-inflammatory and antitumor activities. Geraniol can be used to study diabetes. | ||||||||||||||||||||
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Nerol (Standard) | 98.71% | Nerol (Standard) is the analytical standard of Nerol. This product is intended for research and analytical applications. Nerol is a constituent of neroli oil. Nerol Nerol triggers mitochondrial dysfunction and induces apoptosis via elevation of Ca2+ and ROS. Antifungal activity. | ||||||||||||||||||||
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Citral (Standard) | 98.20% | Citral (Standard) is the analytical standard of Citral. This product is intended for research and analytical applications. Citral is an orally active monoterpene compound in lemon grass essential oil and a natural ALDH1A inhibitor, which can induce apoptosis and cycle arrest in breast cancer cell lines, and has analgesic, anti-injurious and anti-inflammatory effects. | ||||||||||||||||||||
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Sulcatone (Standard) | 99.59% | Sulcatone (Standard) (6-Methyl-5-hepten-2-one (Standard)) is the analytical standard of Sulcatone (HY-W010435). This product is intended for research and analytical applications. Sulcatone (6-Methyl-5-hepten-2-one) is a plant-derived volatile organic compound with activities such as insecticidal, antifungal, and blood pressure-lowering effects. Sulcatone also serves as an insect pheromone and an endogenous metabolite, which can be found in feces. Changes in Sulcatone levels can be used for the auxiliary diagnosis of ulcerative colitis. | ||||||||||||||||||||
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Nerylformate | Nerylformate is a terpenoid derivative secreted by American house dust mites (Dermatophagoides farinae) and European house dust mites (Dermatophagoides pteronyssinus). Nerylformate has a significant attraction effect on both male and female individuals of the two species of house dust mites. Nerylformate guides the mites to gather together to reduce dehydration and enhance defense. Nerylformate can be used for the research of immunology and inflammation, such as allergic rhinitis. | |||||||||||||||||||||
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(3E)-4,8-Dimethylnona-1,3,7-triene | (3E)-4,8-Dimethylnona-1,3,7-triene, a sesquiterpene, is the major herbivore-induced plant volatile that help in defense directly by acting as repellants and indirectly by recruiting insects' natural enemies. (3E)-4,8-Dimethylnona-1,3,7-triene attractes Asian corn borer (ACB, Ostrinia furnacalis) larvae. External supplementation with (3E)-4,8-Dimethylnona-1,3,7-triene hampered the larvae's ability to locate pre-infested maize. | |||||||||||||||||||||
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8-Oxogeranial | 99.89% | 8-Oxogeranial is a monoterpene. The terpenoid is produced by 8-hydroxygeraniol dehydrogenase which uses 8-hydroxygeraniol as its substrate. 8-Oxogeranial is itself a substrate for iridoid synthase which synthesizes cis-trans-iridodial and cis-trans-nepetalactol. | ||||||||||||||||||||
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Deoxygeraniol | 96.67% | Deoxygeraniol, a monoterpenoid, has been reported in Camellia sinensis, Magnolia sieboldii, and Zingiber officinale. It is commonly used as an intermediate in the synthesis of fragrances or flavorings. | ||||||||||||||||||||
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Neral | 97.87% | Neral is a plant-derived anti-inflammatory, antioxidant and anticancer agent. Neral inhibits the phosphorylation of ERK1/2, p38 MAPK and IκB in macrophages induced by LPS (HY-D1056), suppresses the secretion of TNF-α and IL-6, as well as the expression of pro-IL-1β, iNOS and COX-2 in cells, and reduces the production of ROS in cells. Neral inhibits the activation of the NLRP3 inflammasome, and decreases the activation of caspase-1 and the secretion of IL-1β in mouse macrophages. Neral induces autophagy, and exhibits antiproliferative activity both in in vitro breast cancer cell models and mouse xenograft models. Neral regulates brassinosteroid, jasmonic acid and ethylene signaling pathways, and induces the expression of AP2/ERF-ERF and bHLH family genes in rice roots. Neral acts as a herbicide safener, alleviates the damage induced by Fenoxaprop-P-ethyl (HY-B2013), and promotes the elongation of rice roots. Neral can be used in research related to breast cancer, inflammatory and immune system diseases, and herbicide safeners. | ||||||||||||||||||||
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References
- [1]. Liao P C, et al. Anti-inflammatory activity of neral and geranial isolated from fruits of Litsea cubeba Lour[J]. Journal of Functional Foods, 2015, 19: 248-258.
- [2]. Iijima Y, et al. Biosynthesis of geranial, a potent aroma compound in ginger rhizome (Zingiber officinale): molecular cloning and characterization of geraniol dehydrogenase[J]. Plant Biotechnology, 2014, 31(5): 525-534.
