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acylated derivatives

" in MedChemExpress (MCE) Product Catalog:

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製品番号 製品名 Target 研究分野 構造式
  • HY-W402064
    N-Acetyladenosine

    		Nucleoside Antimetabolite/Analog Others
    N-Acetyladenosine is an adenosine analog and an adenosine N 6-acylated derivative. N-Acetyladenosine can be produced via the heterolytic reaction between adenosine and diacetyl peroxide .
    N-Acetyladenosine
  • HY-W015800
    L-Homoserine lactone hydrochloride

    		Drug Intermediate Others
    L-Homoserine lactone hydrochloride is the core structural unit of the bacterial quorum-sensing signal molecule N-acyl-L-homoserine lactone (AHLs). As an important intermediate, L-Homoserine lactone hydrochloride acylated derivatives have potent immunosuppressive activity .
    L-Homoserine lactone hydrochloride
  • HY-W001957
    Glurate

    4-Acetylbutyric acid; 5-Oxohexanoic acid; NSC-5281

    		 Drug Intermediate HIV Infection
    Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid .
    Glurate
  • HY-149997
    Anticancer agent 120

    		Bacterial Reactive Oxygen Species (ROS) Apoptosis Cancer
    Anticancer agent 120 (compound 21) is an N-acylated ciprofloxacin derivative, which has certain antibacterial activity and induces ROS to promote cancer cell apoptosis .
    Anticancer agent 120
  • HY-154862
    Anticancer agent 119

    		Apoptosis Infection Cancer
    Anticancer agent 119 (compound 15) is an N-acylated ciprofloxacin derivative, which has certain antibacterial activity and induces ROS production to promote cancer cell apoptosis .
    Anticancer agent 119
  • HY-154861
    Anticancer agent 118

    		Bacterial Apoptosis Necroptosis Cancer
    Anticancer agent 118, a N‑acylated ciprofloxacin derivative, has anti-bacterial and anticancer activities. Anticancer agent 118 shows high activity against Gram-positive strains and antiproliferative activities against prostate PC3 cells. Anticancer agent 118 can be used for antitumor research .
    Anticancer agent 118
  • HY-W001957R
    Glurate (Standard)

    4-Acetylbutyric acid (Standard); 5-Oxohexanoic acid (Standard); NSC-5281 (Standard)

    		 Reference Standards Drug Intermediate HIV Infection
    Glurate (Standard) is the analytical standard of Glurate (HY-W001957). This product is used for research and analytical applications. Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid .
    Glurate (Standard)
  • HY-W701362
    Glurate-d5

    4-Acetylbutyric acid-d5; 5-Oxohexanoic acid-d5; NSC-5281-d5

    		 Isotope-Labeled Compounds HIV Drug Intermediate Infection
    Glurate-d5 (4-Acetylbutyric acid-d5; 5-Oxohexanoic acid-d5; NSC-5281-d5) is the deuterium labeled Glurate (HY-W001957). Glurate (4-Acetylbutyric acid) is an acylating agent. Glurate can be used in the development of antiviral compounds, especially those targeting retroviruses such as herpes virus and HIV. Glurate can be used in the synthesis of acyclic nucleoside derivatives and 5-hydroxyhexanoic acid .
    Glurate-d5
  • HY-W742094
    Cycotiamine

    		Parasite Infection
    Cycotiamine is an S-acylated thiamine derivative with antiplasmodial activity. Cycotiamine inhibits the proliferation of Plasmodium falciparum and Plasmodium knowlesi. Cycotiamine can be used in malaria-related research .
    Cycotiamine
  • HY-182761
    Antiviral agent 81

    		DNA/RNA Synthesis Cytochrome P450 Flavivirus Influenza Virus Infection
    Antiviral agent 81 is an orally bioavailable N-acylated remdesivir derivative and RdRp inhibitor with 45.3% oral bioavailability (based on active metabolite GS-441524 exposure), plasma half-life >8 h, and reduced CYP3A4 inhibition. Antiviral agent 81 exhibits activity against Coronaviridae, Flaviviridae, and Pneumoviridae, and shows no activity against Orthomyxoviridae, Herpesviridae, and Alphaviridae. Antiviral agent 81 can be used for the research of viral infections .
    Antiviral agent 81

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