Isethionic acid (80% in water)
Based on 1 Customer Validation
Isethionic acid (2-Hydroxyethanesulfonic acid) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis.
For research use only. We do not sell to patients.
- Purity: 80.00%
- CAS No.: 107-36-8
- Formula: C2H6O4S
- Molecular Weight:126.13
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Storage:
Solution, -20°C, 2 years
Biological Activity
Isethionic acid inhibits the attachment of Balanus amphitrite cyprids in a concentration-dependent manner in an in vitro seawater bioassay system, and larval mortality increases at concentrations above 0.01 mg/mL[1].
Isethionic acid can undergo an enzymatic reaction with bile acids under the catalysis of rat liver microsomal preparations to form choyl-ethanesulfonic acid through ester bonds[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Isethionic acid has a higher distribution in cardiac tissue than in muscle at the injection site[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 107-36-8
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Appearance Liquid
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Molecular Weight 126.13
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Formula C2H6O4S
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Color Colorless to light yellow
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SMILES
O=S(CCO)(O)=O
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Synonyms
2-Hydroxyethanesulfonic acid
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (268 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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Handling Instructions (2659 KB)
References
[1]. Hellio C, et al. Isethionic acid and floridoside isolated from the red alga, Grateloupia turuturu, inhibit settlement of Balanus amphitrite cyprid larvae. Biofouling. 2004 Jun;20(3):139-45. [Content Brief]
[3]. Lombardini JB. Enzymatic formation of a cholic acid derivative of isethionic acid. Biochem Pharmacol. 1976 Mar 15;25(6):717-21. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Isethionic acid (80% in water)
- 107-36-8
- 2-Hydroxyethanesulfonic acid
- Endogenous Metabolite
- Parasite
- Balanus amphitrite cyprid larvae
- rat liver microsomal preparations
- Balanus amphitrite nauplius larvae
- Grateloupia turuturu
- cholic acid
- giant squid axoplasm
- taurine
- white mice
- rats
- mammalian tissues
- Inhibitor
- inhibitor
- inhibit