Isethionic acid (80% in water)
Based on 1 Customer Validation
Isethionic acid (2-Hydroxyethanesulfonic acid) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 80.00%
- CAS 番号: 107-36-8
- 分子式: C2H6O4S
- 分子量:126.13
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保管条件:
Solution, -20°C, 2 years
生物活性
製品説明
体外実験
Isethionic acid inhibits the attachment of Balanus amphitrite cyprids in a concentration-dependent manner in an in vitro seawater bioassay system, and larval mortality increases at concentrations above 0.01 mg/mL[1].
Isethionic acid can undergo an enzymatic reaction with bile acids under the catalysis of rat liver microsomal preparations to form choyl-ethanesulfonic acid through ester bonds[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
体内実験
Isethionic acid has a higher distribution in cardiac tissue than in muscle at the injection site[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 107-36-8
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性状 Liquid
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分子量 126.13
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分子式 C2H6O4S
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Color Colorless to light yellow
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SMILES
O=S(CCO)(O)=O
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別名
2-Hydroxyethanesulfonic acid
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Structure Classification
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Solution, -20°C, 2 years
純度とドキュメンテーション
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データシート (268 KB)
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SDS (615 KB)
- English - EN (615 KB)
- Français - FR (615 KB)
- Deutsch - DE (615 KB)
- Norwegian - NO (615 KB)
- Español - ES (615 KB)
- Swedish - SV (615 KB)
- Italian - IT (615 KB)
- Korean - KR (615 KB)
- Portuguese - PT (615 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Hellio C, et al. Isethionic acid and floridoside isolated from the red alga, Grateloupia turuturu, inhibit settlement of Balanus amphitrite cyprid larvae. Biofouling. 2004 Jun;20(3):139-45. [Content Brief]
[3]. Lombardini JB. Enzymatic formation of a cholic acid derivative of isethionic acid. Biochem Pharmacol. 1976 Mar 15;25(6):717-21. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- Isethionic acid (80% in water)
- 107-36-8
- 2-Hydroxyethanesulfonic acid
- Endogenous Metabolite
- Parasite
- Balanus amphitrite cyprid larvae
- rat liver microsomal preparations
- Balanus amphitrite nauplius larvae
- Grateloupia turuturu
- cholic acid
- giant squid axoplasm
- taurine
- white mice
- rats
- mammalian tissues
- Inhibitor
- inhibitor
- inhibit