5 Results for "

aggregated amyloid β-peptide

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "aggregated amyloid β-peptide" in MCE Product Catalog:

Cat. No.: HY-P3688A
Synonyms: Aβ (1-38) TFA; Aβ38 TFA
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-38) (Aβ (1-38)) TFA is a β-Amyloid (Aβ) peptide. β-Amyloid (1-38) TFA interferes with the conversion of Aβ(1-42) to a β-sheet-rich aggregate. β-Amyloid (1-38)TFA reverses the negative impact of Aβ(1-42) on long-term potentiation in acute hippocampal slices and on membrane conductance in primary neurons, and mitigates an Aβ(1-42) phenotype in Caenorhabditis elegans .
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Cat. No.: HY-150049
CAS No.: 1353570-40-7
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

γ-Secretase modulator 13 (compound 4) is a gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 163 nM. γ-Secretase modulator 13 can be used in the study of Alzheimer's disease .
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Cat. No.: HY-P3688
CAS No.: 131438-74-9
Synonyms: Aβ (1-38); Aβ38
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

β-Amyloid (1-38) (Aβ (1-38)) is a β-Amyloid (Aβ) peptide. β-Amyloid (1-38) interferes with the conversion of Aβ(1-42) to a β-sheet-rich aggregate. β-Amyloid (1-38) reverses the negative impact of Aβ(1-42) on long-term potentiation in acute hippocampal slices and on membrane conductance in primary neurons, and mitigates an Aβ(1-42) phenotype in Caenorhabditis elegans .
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Cat. No.: HY-150050
CAS No.: 1353570-53-2
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

gamma-secretase modulator 5 (compound 22d) is a brain-penetrant gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 60 nM. gamma-secretase modulator 5 can be used in the study of Alzheimer's disease .
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Cat. No.: HY-182328
CAS No.: 921193-29-5
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

BTA-EG6 is a brain-penetrant aggregated amyloid-β (Aβ) peptide binder with a Kd of 290 nM for Aβ1-42. BTA-EG6 binds to aggregated Aβ and forms protein-resistive coatings that block interactions between Aβ and catalase. BTA-EG6 protects neuroblastoma cells from Aβ-induced toxicity and oxidative stress, and inhibits Aβ-induced increases in cellular hydrogen peroxide (H2O2) levels. BTA-EG6 can be used for the research of alzheimer’s disease (AD) .
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