1353570-53-2
Chemical Structure
gamma-secretase modulator 5
- CAS No.: 1353570-53-2
- Formula:C22H25N7OS
- Molecular Weight:435.55
IUPAC Name: N-(2-ethyl-4,5,6,7-tetrahydro-2H-indazol-3-yl)-4-(6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl)thiazol-2-amine
InChIKey: JPFIVLHIBZXRKR-UHFFFAOYSA-N
SMILES: CC1=CN(C2=CC=C(C3=CSC(NC4=C5C(CCCC5)=NN4CC)=N3)N=C2OC)C=N1
Biological Activity: gamma-secretase modulator 5 (compound 22d) is a brain-penetrant gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 60 nM. gamma-secretase modulator 5 can be used in the study of Alzheimer's disease[1].
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gamma-secretase modulator 5 | gamma-secretase modulator 5 (compound 22d) is a brain-penetrant gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 60 nM. gamma-secretase modulator 5 can be used in the study of Alzheimer's disease. | |||||||||||||||||||||
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Keywords
