7 Results for "

amyloid β-sheet structures

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "amyloid β-sheet structures" in MCE Product Catalog:

Cat. No.: HY-P4882
CAS No.: 183449-57-2
Target:  

Amyloid-β Tau Protein

Research Areas:  

Neurological Disease

(Pyr3)-Amyloid β-Protein (3-42) is an N-terminally truncated pyroglutamylated β-amyloid peptide. (Pyr3)-Amyloid β-Protein (3-42) forms stable β-sheet structures across different pH values, co-oligomerizes with Aβ1-42 to form cytotoxic oligomers, induces tau-dependent cytotoxicity and neuronal loss, inhibits hippocampal LTP, and exhibits stronger protease resistance. (Pyr3)-Amyloid β-Protein (3-42) exists in the brain tissues of human Alzheimer's disease patients, correlates with the pathogenesis of Alzheimer's disease, and follows a unique, faster oligomerization pathway. (Pyr3)-Amyloid β-Protein (3-42) can be used in Alzheimer's disease-related research .
loading...
    loading...
Cat. No.: HY-P5967
CAS No.: 189064-06-0
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

Acetly-β Amyloid (15-20), Amide is a peptides fragment. Acetly-β Amyloid (15-20), Amide inhibits the β-sheet formation and stabilizes structure of Aβ (1–40) peptide. Acetly-β Amyloid (15-20), Amide can be used in study Alzheimer’s disease .
loading...
    loading...
Cat. No.: HY-P5515
CAS No.: 409085-40-1
Target:  

Inhibitory Antibodies

Research Areas:  

Others

F(N-Me)GA(N-Me)IL is a biological active peptide. (Double N-methylated derivatives of amyloidogenic and cytotoxic partial IAPP sequence were found to be devoid of β-sheet structure, amyloidogenicity and cytotoxicity, The derivatives were able to interact with the native sequences and inhibit amyloid formation)
loading...
    loading...
Cat. No.: HY-P5340
CAS No.: 339091-39-3
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Amyloid-Forming peptide GNNQQNY is a biological active peptide. (This is a heptapeptide from the N-terminal prion-determining domain of the yeast protein Sup35 that forms amyloid fibrils. The availability of its detailed atomic oligomeric structure makes it a good model for studying the early stage of aggregation. The GNNQQNY dimer forms three stable sheet structures. in-register parallel, off-register parallel, and anti-parallel. The in-register parallel dimer, which is close to the amyloid beta-sheet structure, has few interpeptide hydrogen bonds, making hydrophobic interactions more important and increasing the conformational entropy compared to the anti-parallel sheet.)
loading...
    loading...
Cat. No.: HY-161658
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

N-Caffeoyldopamine (Compound 6i) is an amyloid-beta aggregation inhibitor. N-Caffeoyldopamine can inhibit Aβ aggregation to form nano-rod-like structures, thereby preventing β-sheet formation. N-Caffeoyldopamine can be used for Alzheimer's disease research .
loading...
    loading...
Cat. No.: HY-D3430
PTPA-QM is a low-cytotoxicity protein probe that can be used for live-cell imaging and tissue section staining (Lys. Ex/Em = 385/615 nm). PTPA-QM can intercalate into the β-sheet layered structure of β-amyloid fibrils, form intermolecular interactions with amino acid residues, restrict intramolecular rotation and trigger fluorescence activation for imaging purposes. PTPA-QM is applicable to Alzheimer's disease-related research. Maximum excitation/emission wavelength: 448/605 nm .
loading...
    loading...
Cat. No.: HY-DY2023
Target:  

Fluorescent Dye

Research Areas:  

Others

Congo Red Staining Solution (1%) is an absorptive histochemical staining solution based on Congo Red (HY-D0236), which is specifically designed to detect amyloid deposits in tissue sections. When observed under a polarizing microscope, the stained amyloid complexes exhibit characteristic apple-green birefringence, making it a standard tool for the diagnosis of amyloidosis .
loading...
    loading...