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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
angiotensinogen synthesis
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "angiotensinogen synthesis" in MCE Product Catalog:
Cat. No.: HY-147406
CAS No.: 2589926-20-3
Synonyms: ION-904
Target:
Research Areas:
Tonlamarsen (ION-904) is a GalNAc-conjugated antisense oligonucleotide and Angiotensinogen synthesis inhibitor. Tonlamarsen specifically reduces the production of Angiotensinogen in the liver and plasma, and exhibits extremely low activity in the kidneys. Tonlamarsen can be used in research related to hypertension and heart failure .
Cat. No.: HY-147267
CAS No.: 2589926-22-5
Synonyms: ISIS-757456
Target:
Research Areas:
Evazarsen is an angiotensinogen synthesis inhibitor and possesses antihypertensive properties .
Cat. No.: HY-145649A
CAS No.: 2380166-34-5
Synonyms: AD-85481 sodium; ALN-AGT sodium
Research Areas:
Zilebesiran (AD-85481; ALN-AGT) sodium is a long-acting liver-targeted small interfering RNA (siRNA) antihypertensive agent. Zilebesiran sodium binds to the hepatic asialoglycoprotein receptor (ASGPR), activates the RNA-induced silencing complex to degrade hepatic angiotensinogen mRNA, thereby inhibiting the gene expression and synthesis of angiotensinogen. Zilebesiran sodium dose-dependently reduces serum angiotensinogen levels and 24-hour ambulatory blood pressure, with its effect persisting throughout the circadian cycle. Zilebesiran sodium is applicable to research related to hypertension .
Cat. No.: HY-147267A
CAS No.: 2589926-24-7
Synonyms: ISIS-757456 sodium
Target:
Research Areas:
Evazarsen sodium is an angiotensinogen synthesis inhibitor and possesses antihypertensive properties .
Cat. No.: HY-147406A
CAS No.: 2589926-21-4
Synonyms: ION-904 sodium
Target:
Cat. No.: HY-185922
CAS No.: 3080217-81-5
Target:
Research Areas:
Baslisiran is an angiotensinogen (AGT) synthesis inhibitor that can be used in studies related to hypertension .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
