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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
42 Results for "
anxiolytic effect
" in MedChemExpress (MCE) Product Catalog:
Products (42)
42 Results for "anxiolytic effect" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-19801
CAS No.: 1005334-57-5
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CVT-10216 is a highly selective, reversible aldehyde dehydrogenase-2 (ALDH-2) inhibitor with an IC50 of 29 nM. CVT-10216 also has inhibitory effect of ALDH-1 with an IC50 of 1.3 μM. CVT-10216 can reduce excessive alcohol drinking in alcohol-preferring rats and exhibit anxiolytic effects .
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SB-224289 hydrochloride is a selective 5-HT1B receptor antagonist, with anxiolytic effect.
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Hydroxyzine, a benzodiazepine antihistamine agent, acts as an orally active histamine H1-receptor and serotonin antagonist.
Hydroxyzine has anxiolytic effect and can be used for the research of generalised anxiety disorder .
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Hydroxyzine dihydrochloride, a benzodiazepine antihistamine agent, acts as a orally active histamine H1-receptor and serotonin antagonist. Hydroxyzine dihydrochloride has anxiolytic effect and can be used forthe research of generalised anxiety disorder .
Cat. No.: HY-105042
CAS No.: 129954-34-3
Synonyms: Selanc; TP-7
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Cat. No.: HY-P5762
CAS No.: 1415039-79-0
Synonyms: PNX-14
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Cat. No.: HY-105042A
Purity: 99.90%
Synonyms: Selanc diacetate; TP-7 diacetate
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Cat. No.: HY-P5763
CAS No.: 1415039-77-8
Synonyms: PNX-20
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Cat. No.: HY-19490
CAS No.: 669770-29-0
Synonyms: AQW-051
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VQW-765 (AQW-051) is a selective and orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonist with a pKD value of 7.56 to recombinantly expressed human α7-nAChR. VQW-765 shows anxiolytic-like effect in vivo. VQW-765 can be used for the research of anxiety disorder and acute performance anxiety .
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Demoxepam is a major metabolite of Chlordiazepoxide. Demoxepam exhibits cytotoxicity activity against cancer cell lines. Demoxepam has anticonvulsant and anxiolytic effects. Demoxepam has an inhibitory effect on in vitro [ 3H]tryptophan binding to rat hepatic nuclei .
Cat. No.: HY-N8303
CAS No.: 21187-73-5
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Flavonoids Flavones Rutaceae Plants Citrus reticulata Blanco
Synonyms: Ro 11-3128; Ro 11-3128/002
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Meclonazepam (Ro 11-3128) is a benzodiazepine compound with anxiolytic effect . Meclonazepam is active against immature S. mansoni. Meclonazepam (30 μM) eliminates 100% of immature parasites. Meclonazepam has a anti-schistosomal effect .
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SCH 221510 is a potent, orally active and selective NOP (nociceptin opioid receptor) agonist, with an EC50 of 12 nM and Ki of 0.3 nM. SCH 221510 shows an anxiolytic-like effect .
Cat. No.: HY-19686
CAS No.: 95847-70-4
Synonyms: TVX Q 7821 free base
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Ipsapirone (TVX Q 7821) is an anxiolytic compound and a 5-HT1A receptor partial agonist. Ipsapirone (TVX Q 7821) also exhibits 5-HT1A receptor antagonistic effect, and only at high doses it can also produce an inhibitory effect on 5-HT2 and the α1-adrenergic function .
Synonyms: Co 134444
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Posovolone (Co 134444) is an orally active, neuroactive steroid. Posovolone has anticonvulsant and anxiolytic-like activity as well as ataxic effects .
Cat. No.: HY-123840
CAS No.: 461449-78-5
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MRK-623 (Compound 14k) is an orally active, high-affinity GABAA receptor agonist, with the Ki values of 0.85 nM, 3.7 nM, 4.0 nM, and 0.53 nM for α1, α2, α3, and α5, respectively. MRK-623 shows anxiolytic effect .
Cat. No.: HY-101105
CAS No.: 180083-23-2
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SB-224289 is a selective 5-HT1B receptor antagonist, with anxiolytic effect .
Cat. No.: HY-N5126
CAS No.: 62023-90-9
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Cat. No.: HY-N10497
CAS No.: 23255-54-1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
