669770-29-0
669770-29-0
Chemical Structure
VQW-765
Synonym(s): AQW-051
- CAS No.: 669770-29-0
- Formula:C19H22N2O
- Molecular Weight:294.39
IUPAC Name: (R)-3-((6-(p-tolyl)pyridin-3-yl)oxy)quinuclidine
InChIKey: NPDLTEZXGWRMLQ-IBGZPJMESA-N
SMILES: CC1=CC=C(C2=CC=C(O[C@H]3CN4CCC3CC4)C=N2)C=C1
Biological Activity: VQW-765 (AQW-051) is a selective and orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonist with a pKD value of 7.56 to recombinantly expressed human α7-nAChR. VQW-765 shows anxiolytic-like effect in vivo. VQW-765 can be used for the research of anxiety disorder and acute performance anxiety[1].
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VQW-765 | 99.58% | VQW-765 (AQW-051) is a selective and orally active alpha-7 nicotinic acetylcholine receptor (α7-nAChR) agonist with a pKD value of 7.56 to recombinantly expressed human α7-nAChR. VQW-765 shows anxiolytic-like effect in vivo. VQW-765 can be used for the research of anxiety disorder and acute performance anxiety. | ||||||||||||||||||||
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