1. Epigenetics
  2. Histone Demethylase

GSK 690 Hydrochloride 

Cat. No.: HY-117226A
Handling Instructions

GSK 690 (Hydrochloride) is a reversible inhibitor of lysine specific demethylase 1 (LSD1), with a Kd value of 9 nM and a biochemical IC50 of 37 nM.

For research use only. We do not sell to patients.

GSK 690 Hydrochloride Chemical Structure

GSK 690 Hydrochloride Chemical Structure

Size Stock
250 mg Get quote
500 mg Get quote

* Please select Quantity before adding items.

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

GSK 690 (Hydrochloride) is a reversible inhibitor of lysine specific demethylase 1 (LSD1), with a Kd value of 9 nM and a biochemical IC50 of 37 nM.

IC50 & Target

IC50: 37 nM (LSD1), Kd: 8 nM (LSD1)[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4635 mL 12.3177 mL 24.6354 mL
5 mM 0.4927 mL 2.4635 mL 4.9271 mL
10 mM 0.2464 mL 1.2318 mL 2.4635 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

405.92

Formula

C₂₄H₂₄ClN₃O

SMILES

N#CC1=CC=C(C2=CC(OC[[email protected]]3CNCC3)=CN=C2C4=CC=C(C)C=C4)C=C1.Cl

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
GSK 690 Hydrochloride
Cat. No.:
HY-117226A
Quantity:

GSK 690 Hydrochloride

Cat. No.: HY-117226A