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Cat. No.: HY-101105

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SB-224289

Name: SB-224289
Brand: MedChemExpress
SKU: HY-101105
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2 Cited Publications

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Based on 2 publication(s) in Google Scholar

SB-224289 is a selective 5-HT1B receptor antagonist, with anxiolytic effect.

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CAS No.: 180083-23-2
Formule: C₃₂H₃₂N₄O₃
Masse moléculaire:520.62

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

SB-224289 Chemical Structure

CAS No.: 180083-23-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (2)
Pureté et documentation
Références
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Activité biologique

Description

SB-224289 is a selective 5-HT1B receptor antagonist, with anxiolytic effect^[1].

IC₅₀ & Target

5-HT_1B Receptor

Voir tous les produits spécifiques à Isoform 5-HT Receptor :

Chemical Information

CAS No. 180083-23-2
Masse moléculaire 520.62
Formule C₃₂H₃₂N₄O₃
SMILES

O=C(C1=CC=C(C2=CC=C(C3=NOC(C)=N3)C=C2C)C=C1)N4CCC5=C4C=C6C(OCC67CCN(C)CC7)=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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PNAS Nexus

A PITX2-HTR1B pathway regulates the asymmetric development of female gonads in chickens. [Abstract]

2023 Jun 19;2(6):pgad202. PMID: 37388922
Authorea

September 19, 2022.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Cassilly CD, et al. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A. PLoS One. 2016 May 16;11(5):e0154932. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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SB-224289

2 Cited Publications

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Publications (2)
Pureté et documentation
Références

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SB-224289

Publications Citing Use of MedChemExpress (MCE) SB-224289

Voir tous les produits spécifiques à Isoform 5-HT Receptor