129954-34-3
Chemical Structure
Selank
Synonym(s): Selanc; TP-7
- CAS No.: 129954-34-3
- Formula:C33H57N11O9
- Molecular Weight:751.87
IUPAC Name: L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline
InChIKey: JTDTXGMXNXBGBZ-YVHUGQOKSA-N
SMILES: O=C(N1[C@@H](CCC1)C(NCC(N2[C@@H](CCC2)C(O)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H]3N(CCC3)C([C@H](CCCCN)NC([C@@H](N)[C@H](O)C)=O)=O)=O
Biological Activity: Selank (Selanc; TP-7) is a GABAA receptor modulator with anxiolytic activity. Selank allosterically modulates the specific binding of GABA to GABAA receptors and alters the affinity of endogenous ligands for these receptors. Selank reduces elevated anxiety levels, attenuates stress-induced exacerbation of anxiety, and produces a synergistic anxiolytic effect with diazepam. Selank can be used in the research of anxiety disorders[1].
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Selank | 99.80% | Selank (Selanc; TP-7) is a GABAA receptor modulator with anxiolytic activity. Selank allosterically modulates the specific binding of GABA to GABAA receptors and alters the affinity of endogenous ligands for these receptors. Selank reduces elevated anxiety levels, attenuates stress-induced exacerbation of anxiety, and produces a synergistic anxiolytic effect with diazepam. Selank can be used in the research of anxiety disorders. | ||||||||||||||||||||
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Keywords
