129954-34-3
Chemical Structure
Selank
Synonym(s): Selanc; TP-7
- CAS 番号: 129954-34-3
- Formula:C33H57N11O9
- Molecular Weight:751.87
IUPAC Name: L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-proline
InChIKey: JTDTXGMXNXBGBZ-YVHUGQOKSA-N
SMILES: O=C(N1[C@@H](CCC1)C(NCC(N2[C@@H](CCC2)C(O)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H]3N(CCC3)C([C@H](CCCCN)NC([C@@H](N)[C@H](O)C)=O)=O)=O
Biological Activity: Selank (Selanc; TP-7) is a GABAA receptor modulator with anxiolytic activity. Selank allosterically modulates the specific binding of GABA to GABAA receptors and alters the affinity of endogenous ligands for these receptors. Selank reduces elevated anxiety levels, attenuates stress-induced exacerbation of anxiety, and produces a synergistic anxiolytic effect with diazepam. Selank can be used in the research of anxiety disorders[1].
| 製品番号 | 製品名 | 純度 | 製品説明 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Selank | 99.80% | Selank (Selanc; TP-7) is a GABAA receptor modulator with anxiolytic activity. Selank allosterically modulates the specific binding of GABA to GABAA receptors and alters the affinity of endogenous ligands for these receptors. Selank reduces elevated anxiety levels, attenuates stress-induced exacerbation of anxiety, and produces a synergistic anxiolytic effect with diazepam. Selank can be used in the research of anxiety disorders. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
