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Results for "

benzimidazole anthelmintic

" in MedChemExpress (MCE) Product Catalog:

11

Inhibitors & Agonists

1

Isotope-Labeled Compounds

Cat. No. 상품명 Target 연구분야 Chemical Structure
  • HY-B0413
    Fenbendazole
    Maximum Cited Publications
    9 Publications Verification

    		 Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic Infection Cancer
    Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
    Fenbendazole
  • HY-B0413S
    Fenbendazole-d3
    5 Publications Verification

    		 HIF/HIF Prolyl-Hydroxylase Parasite Microtubule/Tubulin Antibiotic Infection
    Fenbendazole-d3 is a deuterium labeled Fenbendazole. Fenbendazole-d3 is a HIF-1α agonist and activates the HIF-1α-related GLUT1 pathway. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
    Fenbendazole-d3
  • HY-B0299
    Oxibendazole
    3 Publications Verification

    		 Parasite Apoptosis Infection Cancer
    Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities .
    Oxibendazole
  • HY-114750
    Mebendazole-amine

    		Drug Metabolite Infection
    Mebendazole-amine is a metabolite of Mebendazole (HY-17595). Mebendazole is a broad-spectrum benzimidazole anthelmintic .
    Mebendazole-amine
  • HY-B0413R
    Fenbendazole (Standard)

    		Reference Standards Parasite HIF/HIF Prolyl-Hydroxylase Microtubule/Tubulin Antibiotic Infection
    Fenbendazole (Standard) is the analytical standard of Fenbendazole. This product is intended for research and analytical applications. Fenbendazole is an orally active benzimidazole anthelmintic agent, with a broad antiparasitic range. Fenbendazole is a microtubule destabilizing agent and acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium. Fenbendazole stabilizes the transcriptional activator HIF-1α. Fenbendazole possesses an efficient anti-proliferative activity and induces apoptosis. Fenbendazole causes cell-cycle arrest and mitotic cell death, and has antitumor activity in mice xenografted with wild-type p53 .
    Fenbendazole (Standard)
  • HY-123305
    5-Hydroxymebendazole

    		Parasite Others
    5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals .
    5-Hydroxymebendazole
  • HY-W011239
    Fenbendazole sulfone

    Oxfendazole sulfone; FBZ-SO2

    		 Parasite Infection
    Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .
    Fenbendazole sulfone
  • HY-B0299R
    Oxibendazole (Standard)

    		Reference Standards Parasite Apoptosis Infection
    Oxibendazole (Standard) is the analytical standard of Oxibendazole. This product is intended for research and analytical applications. Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities .
    Oxibendazole (Standard)
  • HY-W011239R
    Fenbendazole sulfone (Standard)

    Oxfendazole sulfone (Standard); FBZ-SO2 (Standard)

    		 Reference Standards Parasite Infection
    Fenbendazole sulfone (Standard) is the analytical standard of Fenbendazole sulfone. This product is intended for research and analytical applications. Fenbendazole sulfone (Oxfendazole sulfone;FBZ-SO2) is a minor metabolite of Fenbendazole in plasma and is a benzimidazole anthelmintic agent .
    Fenbendazole sulfone (Standard)
  • HY-123305R
    5-Hydroxymebendazole (Standard)

    		Parasite Reference Standards Others
    5-Hydroxymebendazole (Standard) is the analytical standard of 5-Hydroxymebendazole. This product is intended for research and analytical applications. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles. Benzimidazoles are safe, broad-spectrum anthelmintic agents and are widely used for prevention and treatment of parasitic infections in food-producing animals .
    5-Hydroxymebendazole (Standard)
  • HY-158423
    NPD8790

    		Mitochondrial Metabolism Parasite Infection
    NPD8790 is a species selective mitochondrial respiratory complex I inhibitor with an IC50 of 2.4 µM for C. elegans complex I. NPD8790 is more selective for nematode species mitochondria than human, bovine, and mouse mitochondria. NPD8790 is an anthelmintic that kills adult soil-transmitted helminths .
    NPD8790

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