4 Results for "

calf thymus topoisomerase II

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "calf thymus topoisomerase II" in MCE Product Catalog:

Cat. No.: HY-121782
CAS No.: 111279-49-3
Research Areas:  

Infection

A 65281 is a potent DNA gyrase inhibitor with an IC50 value of 0.1 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. A 65281 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL .
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Cat. No.: HY-120747
CAS No.: 135906-72-8
Research Areas:  

Infection

A-65282 is an antibacterial agent. A-65282 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II .
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Cat. No.: HY-118569
CAS No.: 136440-70-5
Research Areas:  

Cancer

CP-115953 is an antitumor fluoroquinolone compound that targets eukaryotic topoisomerase II and Escherichia coli DNA gyrase. CP-115953 inhibits ATP hydrolysis and DNA relaxation by stimulating enzyme-mediated DNA cleavage, and enhances the expression of immune-related cytokines. CP-115953 is applicable for research on human cancers .
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Cat. No.: HY-N21920
CAS No.: 796062-77-6
Dehydrotrametenonic acid is a DNA topoisomerase II inhibitor with an IC50 of 37.5 μM. Dehydrotrametenonic acid inhibits DNA polymerase α and β with IC50 values of 45.5 and 86.5 μM, respectively. Dehydrotrametenonic acid does not intercalate into DNA and exhibits an inhibitory factor-like Topo II inhibition mechanism. Dehydrotrametenonic acid can be used in DNA replication, cell cycle, and cancer-related research .
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