135906-72-8
135906-72-8
Chemical Structure
A-65282
- CAS No.: 135906-72-8
- Formula:C17H16F2N4O2S
- Molecular Weight:378.40
IUPAC Name: 7-(3-aminopyrrolidin-1-yl)-9-cyclopropyl-6,8-difluoroisothiazolo[5,4-b]quinoline-3,4(2H,9H)-dione
InChIKey: NUOJLJDXSSHQBA-UHFFFAOYSA-N
SMILES: O=C1NSC(N(C2CC2)C3=C4C=C(F)C(N5CC(N)CC5)=C3F)=C1C4=O
Biological Activity: A-65282 is an antibacterial agent. A-65282 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II[1].
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A-65282 | A-65282 is an antibacterial agent. A-65282 inhibits P4 DNA unknotting with an IC50 value of 8 µg/mL. A 65281 induces DNA breakage mediated by calf thymus topoisomerase II. | |||||||||||||||||||||
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References
Keywords
