57 Results for "

carbamoyl

" in MedChemExpress (MCE) Product Catalog:
Products (57)

57 Results for "carbamoyl" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-B0711
CAS No.: 1188-38-1
Synonyms: N-Carbamyl-L-glutamic acid
Research Areas:  

Infection Cancer

Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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2
2 Cited Publications
Cat. No.: HY-136128
CAS No.: 2194903-42-7
Purity:  98.36%
H3B-120 is a highly selective, competitive and allosteric carbamoyl phosphate synthetase 1 (CPS1) inhibitor with an IC50 of 1.5 μM and a Ki of 1.4 μM. H3B-120 has anti-cancer activity .
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2
2 Cited Publications
Cat. No.: HY-P5126
CAS No.: 1192362-32-5
DOTA-LM3 is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 and 68 Ga-DOTA-LM3. 68 Ga-DOTA-LM3 shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis . DOTA-LM3 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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2
2 Cited Publications
Cat. No.: HY-P5126A
DOTA-LM3 TFA is a somatostatin receptor (SSTR) antagonist. LM3 refers to p-Cl-Phe- cyclo(D-Cys-Tyr-D-4-amino-Phe(carbamoyl)-Lys-Thr-Cys)D-Tyr- NH2, as well as a somatostatin antagonist. DOTA-LM3 TFA is often isotopically labeled for tracing tumors in vivo, such as 177Lu-DOTA-LM3 TFA and 68 Ga-DOTA-LM3 TFA. 68 Ga-DOTA-LM3 TFA shows favorable biodistribution, high tumor uptake, good tumor retention, and few safety concerns. 177Lu-DOTA-LM3 TFA can be used for research in DOTATOC-negative liver metastases, such as pancreatic NET and extensive tumor thrombosis . DOTA-LM3 (TFA) can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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1
1 Cited Publications
Cat. No.: HY-P5128
CAS No.: 1039726-31-2
Synonyms: Satoreotide tetraxetan
DOTA-JR11 is a somatostatin receptor 2 (SSTR2)antagonist. DOTA-JR11 can be labeled by 68Ga, used for paired imaging in neuroendocrine tumors (NETs) research . DOTA-JR11 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs).
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1
1 Cited Publications
Cat. No.: HY-128425A
CAS No.: 13184-27-5
Purity:  ≥98.0%
Synonyms: L-Ureidosuccinic acid
N-Carbamoyl-L-aspartic acid (L-Ureidosuccinic acid) is an important pyrimidine metabolic precursor and intermediate metabolite. N-Carbamoyl-L-aspartic acid reverses the growth inhibition of Ura + strains induced by 2-thiouracil (with growth rate increasing linearly with its concentration), but fails to support the growth of uracil-requiring Ura - strains. N-Carbamoyl-L-aspartic acid inhibits the cell growth of *Saccharomyces cerevisiae* by suppressing the purine biosynthetic pathway at a pre-step of 5-aminoimidazole nucleotide synthesis. The growth inhibitory effect of N-Carbamoyl-L-aspartic acid on yeast can be alleviated by purines, and the sensitivity of strains is closely related to the activity level of dihydroorotase .
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Cat. No.: HY-128425
CAS No.: 923-37-5
Purity:  99.92%
Synonyms: Ureidosuccinic Acid
N-​Carbamoyl-​DL-​aspartic acid (Ureidosuccinic acid) is a precursor of nucleic acid pyrimidines. N-​Carbamoyl-​DL-​aspartic acid has antitumor activities .
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Cat. No.: HY-140459
CAS No.: 846549-37-9
Purity:  98.59%
Target:  

PROTAC Linkers

Research Areas:  

Cancer

2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . 2-((Azido-PEG8-carbamoyl)methoxy)acetic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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Cat. No.: HY-79680
CAS No.: 623950-02-7
Research Areas:  

Others

(S)-2-(tert-butoxycarbonylamino)-3-(4-carbamoyl-2,6-dimethylphenyl)propanoic acid is a phenylalanine derivative .
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Cat. No.: HY-P5362
NODAGA-LM3 is a ligand that can cross the blood-brain barrier and targets somatostatin receptor SSTR2 with high affinity (IC50 = 1.3 nM). NODAGA-LM3 does not trigger the internalization of SSTR2 and can inhibit agonist-induced internalization processes. NODAGA-LM3 shows low uptake in normal tissues such as the liver and spleen, but high uptake in the lungs and blood pool. 68Ga-labeled NODAGA-LM3 can serve as a PET imaging agent for well-differentiated neuroendocrine tumors, and is applied in studies related to small cell lung cancer and well-differentiated neuroendocrine tumors .
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Cat. No.: HY-P10137
CAS No.: 1801415-23-5
Synonyms: JR11
Satoreotide (JR11) is a somatostatin receptor subtype 2 (sstr2)-selective antagonist. Satoreotide can be used as a PET imaging agent when labeled with 68Ga. Satoreotide can be used for cancer research .
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Cat. No.: HY-P1726
CAS No.: 1416983-77-1
MSG606 is a selective melanocortin 1 receptor (MC1R) antagonist. MSG606 can abolish the neuroprotective effects of BMS-470539 (HY-15616) (MC1R agonist). MSG606 can inhibit cancer cell proliferation and transition from the G1 to the S phase. MSG606 can delay pain hypersensitivity and reduce cholesterol levels. MSG606 can be used for the researches of cancer, inflammation, neurological and metabolic disease, such as breast cancer and subarachnoid hemorrhage (SAH) .
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Cat. No.: HY-153459
CAS No.: 2684292-71-3
Purity:  98.83%
Research Areas:  

Cancer

IBG1 is a bivalent molecular glue degrader targeting BRD2/BRD4, with IC50 values of 12.8 nM and 462 nM, respectively, and an EC50 of 44 nM. By binding to the adjacent BD1 and BD2 bromodomains of BRD2 and BRD4, IBG1 stabilizes the ternary complex formed with DCAF16, thereby driving CRL-mediated ubiquitination and proteasomal degradation. IBG1 induces cancer cell apoptosis and inhibits cancer cell growth in a DCAF16-dependent manner, and downregulates MYC expression through DCAF16-independent BET bromodomain inhibition. IBG1 can be used in research of various cancers including prostate cancer .
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Cat. No.: HY-160610A
CAS No.: 1866-68-8
Target:  

Drug Derivative

Research Areas:  

Others

Carbamoyl phosphate dilithium salt is an antisickling agent and plays a significant role in the urea cycle. Carbamoyl phosphate dilithium salt carbamylates the amino-terminal valine residues of hemoglobin S in erythrocytes, which interferes with the sickling phenomenon. Carbamoyl phosphate dilithium salt exhibits toxicity due to the lithium cation .
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Cat. No.: HY-W009418S
1-Methylnicotinamide- 13C,d3 (iodide) is the 13C- and deuterium labeled 3-Carbamoyl-1-methylpyridin-1-ium iodide .
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Cat. No.: HY-128425R
CAS No.: 923-37-5
Synonyms: Ureidosuccinic acid (Standard)
N-​Carbamoyl-​DL-​aspartic acid (Standard) (Ureidosuccinic acid (Standard)) is the analytical standard of N-​Carbamoyl-​DL-​aspartic acid (HY-128425). This product is intended for research and analytical applications. N-​Carbamoyl-​DL-​aspartic acid is a precursor of nucleic acid pyrimidines. N-​Carbamoyl-​DL-​aspartic acid has antitumor activities.
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Cat. No.: HY-I0004
CAS No.: 134002-26-9
Target:  

Drug Intermediate

Research Areas:  

Others

3-(S)-(1-Carbamoyl-1,1-diphenylmethyl)pyrrolidine tartrate is a drug intermediate for synthesis of various active compounds.
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Cat. No.: HY-B0711R
CAS No.: 1188-38-1
Synonyms: N-Carbamyl-L-glutamic acid (Standard)
Carglumic Acid (Standard) is the analytical standard of Carglumic Acid. This product is intended for research and analytical applications. Carglumic acid (N-Carbamyl-L-glutamic acid), a functional analogue of N-acetylglutamate (NAG) and a carbamoyl phosphate synthetase 1 (CPS1) activator, is used to treat acute and chronic hyperammonemia associated with NAG synthase (NAGS) deficiency.
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Cat. No.: HY-149664
CAS No.: 137056-72-5
Synonyms: DC-Chol
Target:  

Liposome

Research Areas:  

Cancer

3β-[N-(N′,N′-Dimethylaminoethyl)carbamoyl]cholesterol, a lipid, has been investigated in cancer gene therapy and vaccine delivery system .
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Cat. No.: HY-P4756
CAS No.: 282725-67-1
Target:  

Inhibitory Antibodies

Research Areas:  

Others

N-(2-Carbamoyl-ethyl)-Val-Leu-anilide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .
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