4 Results for "

chiral purity

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "chiral purity" in MCE Product Catalog:

Cat. No.: HY-I0169
CAS No.: 196601-69-1
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

(R)-Amino-N-benzyl-3-methoxypropionamide is a key intermediate for the synthesis of the antiepileptic agent (R)-Lacosamide. To improve its chiral purity and chemical stability, (R)-Amino-N-benzyl-3-methoxypropionamide can react with phosphoric acid to form a phosphate salt. Detected by high performance liquid chromatography (HPLC), this phosphate salt exhibits extremely high chiral purity, with the content of the R-enantiomer reaching up to 99.37% .
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Cat. No.: HY-W001069
CAS No.: 192139-92-7
Synonyms: RuCl[(R,R)-Tsdpen](p-cymene)
RuCl (p-cymene)[(R,R)-Ts-DPEN] (RuCl[(R,R)-Tsdpen](p-cymene)) is a Noyori-type chiral ruthenium asymmetric transfer hydrogenation catalyst. RuCl (p-cymene)[(R,R)-Ts-DPEN] is widely used in the asymmetric transfer hydrogenation and enantioselective reduction of ketones, imines and quinolines to construct specific stereoisomers with high optical purity .
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Cat. No.: HY-34849
CAS No.: 53531-34-3
Research Areas:  

Others

(R)-(-)-1-(9-Anthryl)-2,2,2-trifluoroethanol is utilized as a chiral shift reagent for determining enantiomeric ratios. Additionally, (R)-(-)-1-(9-Anthryl)-2,2,2-trifluoroethanol can be employed for nuclear magnetic resonance (NMR) optical purity determination .
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Cat. No.: HY-L903
5,281 compounds

Fragment-based drug discovery (FBDD) is well suited for discovering both drug leads and chemical probes of protein function. 3-dimensionality (3D) diversity is pivotal because the molecular shape is one of the most important factors in molecular recognition by a biomolecule. There is a developing appreciation that 3D fragments could offer opportunities that are not provided by 2D fragments.

MCE 3D Diverse Fragment Library consists of 5,400 non-flat fragment-like molecules (average Fsp3 value 0.58). More than 4,700 fragment compounds contain at least one chiral center in the structure. The key concepts that underlie the library design were 3D shape, structural diversity, reactive functionality and fragment-like. This 3D Diverse Fragment Library brings higher fragment hit optimization and increases the likelihood to find innovative hits in FBDD.