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Results for "

condensation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	ADC Payload (1) Antibiotic (2) Apoptosis (11) Bacterial (7) Bcl-2 Family (1) Biochemical Assay Reagents (37) Btk (1) Caspase (6) Cathepsin (1) Ceramidase (1) Chloride Channel (2) DNA Alkylator/Crosslinker (1) DNA Methyltransferase (3) DNA/RNA Synthesis (6) Dopamine Receptor (1) Drug Derivative (2) Drug Intermediate (5) Drug Metabolite (1) Drug-Linker Conjugates for ADC (1) Endogenous Metabolite (17) Environmental Pollutants (4) Ferroptosis (1) Fluorescent Dye (8) Free Fatty Acid Receptor (1) Fructose-1,6-bisphosphate aldolase (1) Fungal (1) GABA Receptor (1) Glutathione Peroxidase (2) Glycosidase (1) HDAC (1) Histone Methyltransferase (1) HIV (1) Isotope-Labeled Compounds (4) Lipoxygenase (1) MDM-2/p53 (1) Mitochondrial Metabolism (4) NO Synthase (2) Nucleoside Antimetabolite/Analog (2) Parasite (4) PARP (1) Peptide-Drug Conjugates (PDCs) (1) Phospholipase (1) PPAR (1) Reactive Oxygen Species (ROS) (3) Reference Standards (9) Small Interfering RNA (siRNA) (1) SOD (1) Sodium Channel (1) Thymidylate Synthase (1) TRP Channel (1) Tyrosinase (1)
By Research Areas:	Cancer (22) Cardiovascular Disease (1) Infection (12) Inflammation/Immunology (9) Metabolic Disease (24) Neurological Disease (7)
Oligonucleotides:	Solvents (1) Adenosine (1) Nucleoside Analogs (1) Polymers (1)

114

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-129905

L-Leucyl-L-Leucine methyl ester hydrochloride Maximum Cited Publications 18 Publications Verification LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride	Endogenous Metabolite	Inflammation/Immunology
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress .

HY-129905A

L-Leucyl-L-Leucine methyl ester hydrobromide Maximum Cited Publications 18 Publications Verification LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide	Endogenous Metabolite	Inflammation/Immunology
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress .

HY-B1142

Lipoamide 5+ Cited Publications (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide	NO Synthase	Others
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-162288

FAZ-3532 4 Publications Verification	DNA/RNA Synthesis	Cancer
FAZ-3532 is a G3BP inhibitor (K_d = 0.54 μM) which binds to the NTF2L nsP3 binding pocket in G3BP1. FAZ-3532 disrupts the co-condensation of RNA, G3BP1, and caprin 1. FAZ-3532 inhibits G3BP-driven stress granule formation. FAZ-3532 can be studied as a powerful tool to probe the biology of stress granules and a promising interventions designed to modulate stress granule formation .

HY-N7103

Ethyl oleate	Environmental Pollutants Endogenous Metabolite	Others
Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .

HY-Y1666

2,2′-Dipyridyl disulfide	Biochemical Assay Reagents	Others
2,2′-Dipyridyl disulfide is a useful reagent for the determination of sulfhydryl groups. 2,2′-Dipyridyl disulfide is a common reagent in peptide chemistry, often used in oxidation–reduction condensations to form peptide bonds or in coupling reactions to form disulfide-linked heterodimers .

HY-130592

Compound 48/80 trihydrochloride 5 Publications Verification C48/80 trihydrochloride	Phospholipase	Neurological Disease
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde. Compound 48/80 trihydrochloride is also a histamine releaser and a mast cell degranulator. Compound 48/80 inhibits phosphatidylinositol-specific phospholipase C activity from human platelets .

HY-B0837

Emamectin Benzoate 1 Publications Verification MK-244	Environmental Pollutants Parasite Apoptosis Reactive Oxygen Species (ROS) GABA Receptor	Infection Neurological Disease
Emamectin Benzoate (MK-244) is an orally active nervoussystem toxicant by binding g-aminobutyric (GABA) receptor in insects. Emamectin Benzoate is one of semi-synthetic derivative of Avermectin (HY-15311) with a broadspectrum of insecticidal and acaricidal activity. Emamectin Benzoate induces ROS-mediated DNA damage and cell apoptosis. Emamectin Benzoate, a mixture of the natural Emamectin B1a benzoate and Emamectin B1b benzoate, has the main component of Emamectin B1a benzoate .

HY-P2739

Citrate synthase	Endogenous Metabolite	Others
Citrate synthase is responsible for catalyzing the first reaction of the citric acid cycle: the condensation of acetyl-CoA and oxaloacetate to form citrate. Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix .

HY-N13356

L-gamma-Glutamyl-L-threonine gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr	Bacterial Peptide-Drug Conjugates (PDCs) Drug Metabolite	Infection Inflammation/Immunology
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .

HY-Y1078

DMF-DMA N-Dimethoxymethyl-N,N-dimethylamine	Biochemical Assay Reagents	Others
DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .

HY-W017446

4-Formylbenzoic acid Tetraphthalaldehydic acid	Biochemical Assay Reagents	Others
4-Formylbenzoic acid is an intermediate in the synthesis of terepthalic acid. 4-Formylbenzoic acid can react with barium carbonate to yield two-dimensional barium(II) coordination polymer. 4-Formylbenzoic acid can also be used in the synthesis of acid functionalized mesoporous silica catalyst via the condensation .

HY-W011548

2-Aminoadenosine	Nucleoside Antimetabolite/Analog	Others
2-Aminoadenosine is a modified adenine base and adenosine analog that stabilizes RNA duplexes and enhances template-directed nucleotide condensation reactions. 2-Aminoadenosine forms three hydrogen bonds with uracil to increase the melting temperature of hybrid strands, thereby stabilizing uracil-containing RNA duplexes .

HY-157068

icFSP1	Ferroptosis Glutathione Peroxidase	Cancer
icFSP1 is a potent ferroptosis suppressor protein-1 (FSP1) inhibitor. icFSP1 triggers subcellular relocalization of FSP1 from the membrane and FSP1 condensation, in synergism with GPX4 inhibition. icFSP1 induces ferroptosis. icFSP1 shows antitumor activity against melanoma. .

HY-W014940

Ethylene glycol dimethacrylate	Reactive Oxygen Species (ROS) Apoptosis Glutathione Peroxidase SOD	Others
Ethylene glycol dimethacrylate is a diester formed by the condensation of Ethylene glycol (HY-Y0338) and Methacrylic acid. Ethylene glycol dimethacrylate is a cross-linking agent for polymers. Ethylene glycol dimethacrylate increases Apoptosis, GPx4, SOD2, ROS. Ethylene glycol dimethacrylate is cytotoxic and genotoxic. Ethylene glycol dimethacrylate exhibits cross-linking activity, enhancing the mechanical properties and stability of materials .

HY-W004289

Methyl pentadecanoate	Drug Derivative	Others
Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol .

HY-W009823

Phenyl benzoate	Chloride Channel	Others
Phenyl benzoate is a benzoate ester obtained by the formal condensation of phenol with benzoic acid. Phenyl benzoate is a chloride transport blocker, inhibits Cl ^--dependent Glu accumulation into vesicles. Phenyl benzoate can be used as preservative in cosmetic products .

HY-W206168

Tetrahydropapaveroline hydrobromide Norlaudanosoline hydrobromide	Dopamine Receptor	Neurological Disease
Tetrahydropapaveroline (Norlaudanosoline) hydrobromide, an isoquinoline alkaloid, is a condensation product of dopamine and dopaldehyde. Tetrahydropapaveroline hydrobromide inhibits [ ³H]DA uptake with a K_i of 41 μM. Tetrahydropapaveroline hydrobromide can be used for the study of Parkinson's disease and/or alcohol addiction .

HY-141591

CYT296	Biochemical Assay Reagents	Others
CYT296 is a target chromatin de-condensation compound. CYT296 can improve the induction of induced pluripotent stem cell (iPSCs) mediated by defined factors (OSKM) and induce an open chromatin state in Mouse Embryonic Fibroblast (MEFs) to facilitate somatic cell reprogramming. CYT296 can be used for cell replacement therapies and drug screening research .

HY-W090942

Z-Gly-Gly-Phe-OH	Endogenous Metabolite Sodium Channel	Others
Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC₅₀ of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis .

HY-N1915

Cellohexaose	Endogenous Metabolite	Metabolic Disease
Cellohexaose is a glucose polymer with two or more glucose monomers produced from the breakdown of cellulose, consisting of a condensation of beta (1-4) linked D-glucose monomers .

HY-W688565

(2S)-2-Amino-1-hydroxyoctadecan-3-one	Ceramidase	Metabolic Disease
(2S)-2-Amino-1-hydroxyoctadecan-3-one is the product generated by the decarboxylative condensation of L-serine and palmitoyl-CoA catalyzed by serine palmitoyltransferase (SPT) .

HY-W068700

Methyl sorbate	Biochemical Assay Reagents	Others
Methyl sorbate, which is an ester formed by the condensation of methanol and hexa-2,4-dienoic acid, is commonly used as a flavoring agent and fragrance in the food and cosmetic industries due to its fruity, floral, and taste, and in addition , it has also been investigated for its potential use as a starting material in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and polymers.

HY-W076441

Ethyl (S)-3-hydroxybutanoate Ethyl (S)-3-hydroxybutyrate	Biochemical Assay Reagents	Others
Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.

HY-N2037C

(S)-Higenamine hydrobromide 1 Publications Verification (S)-Norcoclaurine hydrobromide	Endogenous Metabolite	Others
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N2592

Isobutylshikonin	Others	Inflammation/Immunology
Isobutylshikonin is a kind of shikonin pigments found in hairy root culture of Lithospermum canescens. Isobutylshikonin decreases cell viability induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (HY-D1056) .

HY-W102375

4-Acetoxycinnamic acid	Drug Intermediate	Inflammation/Immunology
4-Acetoxycinnamic acid is an acetate ester obtained by the formal condensation of the hydroxy group of trans-4-coumaric acid with acetic acid. 4-Acetoxycinnamic acid is a member of cinnamic acids and a member of phenyl acetates. 4-Acetoxycinnamic acid derives from a trans-4-coumaric acid .

HY-Y0198

2,6-Diaminopyridine	Biochemical Assay Reagents Drug Intermediate	Neurological Disease
2,6-Diaminopyridine is an intermediate and coupling agent for hair dyes. 2,6-Diaminopyridine participates in organic synthesis reactions such as N-methylation and can bind metal ions by forming macrocyclic ligands through condensation with aldehydes. 2,6-Diaminopyridine can be used to synthesize the analgesic phenazopyridine hydrochloride (HY-B0985) .

HY-E70523

Pentanoyl coenzyme A Valeryl-CoA; Valeryl-coenzyme A; Pentanoyl coenzyme A free acid	Endogenous Metabolite	Metabolic Disease
Pentanoyl coenzyme A (Valeryl-CoA) is a short-chain fatty acyl-CoA that functions as an intermediate in mitochondrial β-oxidation and related metabolic pathways. Pentanoyl coenzyme A results from the formal condensation of the thiol group of coenzyme A with the carboxy group of pentanoic acid. Pentanoyl coenzyme A's levels can reflect changes in lipid metabolism under different physiological and pathological conditions. Pentanoyl coenzyme A can be used for research on lipid metabolism .

HY-W009411

Dansyl hydrazine	Fluorescent Dye	Others
Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease .

HY-121199

Germanicol	Apoptosis	Cancer
Germanicol is a selective antineoplastic agent against human colon cancer cell lines HCT-116 and HT29 . Germanicol induces apoptosis via chromatin condensation and DNA damage .

HY-E70078

Cystathionine β-synthase	Biochemical Assay Reagents	Others
Cystathionine β-synthase is an enzyme that catalyzes the condensation of serine and homocysteine to water and cystathionine. Cystathionine β-synthase is a prominent enzyme for the production of hydrogen sulfide (H₂S) .

HY-P2977

N-Acetylneuraminate lyase (CgNal) Sialic acid aldolase (CgNal)	Fructose-1,6-bisphosphate aldolase Endogenous Metabolite	Others
N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)) is a class I aldolase, is often used in biochemical studies. N-Acetylneuraminate lyase (CgNal) catalyzes the reversible condensation of pyruvate with N-acetyl-d-mannosamine (ManNAc) to yield the sialic acid N-acetylneuraminic acid (Neu5Ac) .

HY-E70016

Terminal deoxyribonucleotidyltransferase TdT	DNA/RNA Synthesis	Others Cancer
Terminal deoxyribonucleotidyltransferase (TdT) catalyses the condensation of deoxyribonucleotide triphosphates onto the 3' hydroxyl ends of DNA strands and adds N-regions to gene segment junctions during V(D)J recombination. Terminal deoxyribonucleotidyltransferase is expressed in immature, pre-B, pre-T lymphoid cells, and acute lymphoblastic leukemia/lymphoma cells .

HY-W005176

Methyl 3-oxohexanoate Methyl Butyrylacetate; Methyl 3-oxohexanoate	Biochemical Assay Reagents	Others
Methyl 3-oxohexanoate (Methyl Butyrylacetate) is an organic compound commonly used in the manufacture of fragrances, drugs, and other chemicals. It can be used as a condensation reagent, a diazotization reagent and an addition reagent, and it plays a catalytic role in some organic synthesis reactions, and can also play a role in some drug synthesis. In addition, the compound is widely used in the food industry, for example in products such as juices, beer and confectionery.

HY-N7103R

Ethyl oleate (Standard)	Reference Standards Endogenous Metabolite	Others
Ethyl oleate (Standard) is the analytical standard of Ethyl oleate. This product is intended for research and analytical applications. Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .

HY-W009048

Dicyclohexano-18-crown-6-ether DCH18C6; Perhydrodibenzo-18-crown-6	Biochemical Assay Reagents	Others
Dicyclohexano-18-crown-6-ether (DCH18C6) is an excellent strontium chelating agent. Dicyclohexano-18-crown-6-ether exhibits favorable extraction capacity and selectivity toward Sr (II). After chemical modification, Dicyclohexano-18-crown-6-ether is covalently bonded to an organosilicon matrix via co-condensation. DCH18C6-functionalized organosilicon materials are expected to be applied to the extraction and separation of strontium from radioactive waste liquid .

HY-178106

SCN2	Drug Intermediate	Cancer
SCN2 is a esterase-responsive prodrug-based amphiphile composed of SN38 (HY-13704) and di-(triazole-[12]aneN3, N) moiety through a 7‑carbon alkyl chains. SCN2 has excellent self-assembly and reversible siRNA condensation capabilities as well as anti-proliferation activity against cancer cells. SCN2 can be used for synthesis of nanoparticles for drug delivery of lung cancer .

HY-134428

Arachidonoyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-N2037B

(S)-Higenamine (S)-Norcoclaurine	Endogenous Metabolite	Others
(S)-Higenamine ((S)-Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-146128

Anti-hyperglycemic agent-1	Glycosidase	Metabolic Disease
Anti-hyperglycemic agent-1 (compound 10) is a potent α-Glucosidase inhibitor, with an IC₅₀ of 0.53 μM. Anti-hyperglycemic agent-1 can be used for diabetes research .

HY-N7497

Protoescigenin	Others	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-D2101

TAMRA-PEG3-NH2	Fluorescent Dye	Others
TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-Y1624

1,1'-(Azodicarbonyl)-dipiperidine ADDP; SR 4077	Free Fatty Acid Receptor PPAR	Metabolic Disease
1,1'-(Azodicarbonyl)-dipiperidine (ADDP) can be used in the condensation reaction of alcohols with acidic compounds. 1,1'-(Azodicarbonyl)-dipiperidine can also be used in the synthesis of GPR120 agonists with antidiabetic activity, as well as the synthesis of triple agonists for PPARα, PPARγ, and PPARδ. 1,1'-(Azodicarbonyl)-dipiperidine can be used in metabolic disease research .

HY-W099586

Ethyl tetradecanoate Myristic acid ethyl ester	Environmental Pollutants	Others
Ethyl tetradecanoate, which is an ester formed by the condensation of ethanol and myristic acid, is commonly used as a flavoring agent and fragrance in the food and cosmetic industries.

HY-CE00380

(S)-3-Hydroxyoctanoyl-CoA (S)-3-Hydroxyoctanoyl-Coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(S)-3-Hydroxyoctanoyl-CoA ((S)-3-Hydroxyoctanoyl-Coenzyme A) is a hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (S)-3-hydroxyoctanoic acid.

HY-CE00475

(R)-3-Hydroxytetradecanoyl-CoA (R)-3-Hydroxytetradecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(R)-3-Hydroxytetradecanoyl-CoA ((R)-3-Hydroxytetradecanoyl-coenzyme A) is a 3-hydroxy fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A with the carboxy group of (R)-3-hydroxytetradecanoic acid.

HY-W068214

Methyl undec-10-enoate Methyl-10-undecenoate	Environmental Pollutants Biochemical Assay Reagents	Others
Methyl undec-10-enoate, which is an ester formed by the condensation of methanol and undec-10-enoic acid, is commonly used as a flavoring and fragrance in the food and cosmetic industries due to its sweet fruity smell and taste , in addition, its potential use in biofuel production and as a starting material for the synthesis of various organic compounds was investigated.

HY-D2102

TAMRA-PEG7-NH2	Fluorescent Dye	Others
TAMRA-PEG7-NH2 is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-D2154

AF 430 carboxylic acid dipotassium	Fluorescent Dye	Others
AF 430 carboxylic acid is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 carboxylic acid can form covalent bonds through a condensation reaction between carboxylic acid groups and molecules containing amino groups. To achieve specific coupling of dye labels and biomolecules .

Cat. No.	Product Name

HY-L098

Drug Metabolite Library

415 compounds

A drug metabolite is a byproduct of the body breaking down, or “metabolizing” a drug into a different substance. Most drugs undergo chemical alteration by various bodily systems as a way to create compounds that are more easily excreted from the body. Drugs can be metabolized by oxidation, reduction, hydrolysis, hydration, conjugation, condensation, or isomerization. Drug metabolism can produce metabolites with physicochemical and pharmacological properties that differ substantially from those of the parent drug, and consequently have important implications for both drug safety and efficacy.

MCE offers a unique collection of 415 drug metabolites which is a useful tool for drug safety and efficacy study and drug repurposing.

Cat. No.	Product Name	Type

HY-D2101

TAMRA-PEG3-NH2	Fluorescent Dyes
TAMRA-PEG3-NH2 is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-D2102

TAMRA-PEG7-NH2	Fluorescent Dyes
TAMRA-PEG7-NH2 is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-D2154

AF 430 carboxylic acid dipotassium	Fluorescent Dyes
AF 430 carboxylic acid is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 carboxylic acid can form covalent bonds through a condensation reaction between carboxylic acid groups and molecules containing amino groups. To achieve specific coupling of dye labels and biomolecules .

HY-D1324

Cyanine5.5 hydrazide dichloride	Fluorescent Dyes
Cyanine5.5 hydrazide, an analog of Cyanine5.5 fluorophore, is a near-infrared (NIR) fluorescent dye. Cyanine5.5 hydrazide is used for labeling of biomolecules through the condensation between the hydrazide groups and the carbonyl groups. (λ_ex=684 nm, λ_em=710 nm) .

HY-D2098

TAMRA-PEG2-NH2	Fluorescent Dyes
TAMRA-PEG2-NH2 is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-NH2 contains NH2 groups, which can undergo condensation reactions with carboxyl groups to form covalent bonds.

HY-D2163

AF 430 amine	Fluorescent Dyes
AF 430 amine is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 amine can form covalent bonds through a condensation reaction between amino groups and molecules containing carboxyl groups. To achieve specific coupling of dye labels and biomolecules .

Cat. No.	Product Name	Type

HY-W105426

3-(Trimethoxysilyl)propyl methacrylate [3-(Methacryloyloxy)propyl]trimethoxysilane	Biochemical Assay Reagents
3-(Trimethoxysilyl)propyl methacrylate ([3-(Methacryloyloxy)propyl]trimethoxysilane) is a reactive monomer and silane coupling agent with C=C and O-C=O functional groups, acting as a surface modifier and anti-agglomeration agent. 3-(Trimethoxysilyl)propyl methacrylate can be used to prepare nanoparticles .

HY-155882

mPEG750-amine

mPEG750-NH2

Biochemical Assay Reagents

mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .

HY-W017446

4-Formylbenzoic acid Tetraphthalaldehydic acid	Biochemical Assay Reagents
4-Formylbenzoic acid is an intermediate in the synthesis of terepthalic acid. 4-Formylbenzoic acid can react with barium carbonate to yield two-dimensional barium(II) coordination polymer. 4-Formylbenzoic acid can also be used in the synthesis of acid functionalized mesoporous silica catalyst via the condensation .

HY-W068700

Methyl sorbate

Biochemical Assay Reagents

Methyl sorbate, which is an ester formed by the condensation of methanol and hexa-2,4-dienoic acid, is commonly used as a flavoring agent and fragrance in the food and cosmetic industries due to its fruity, floral, and taste, and in addition , it has also been investigated for its potential use as a starting material in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and polymers.

HY-W076441

Ethyl (S)-3-hydroxybutanoate

Ethyl (S)-3-hydroxybutyrate

Biochemical Assay Reagents

Ethyl (S)-3-hydroxybutanoate, also known as (S)-ethyl lactate, which is an ester formed by the condensation of ethanol and (S)-3-hydroxybutanoate, is known for its fruity, sweet smell and taste , which are commonly used as flavoring agents and fragrances in the food and cosmetic industries, and in addition, its potential use as a starting material for the synthesis of various organic compounds, including pharmaceuticals and agrochemicals, has been investigated.

HY-Y0198

2,6-Diaminopyridine	Biochemical Assay Reagents
2,6-Diaminopyridine is an intermediate and coupling agent for hair dyes. 2,6-Diaminopyridine participates in organic synthesis reactions such as N-methylation and can bind metal ions by forming macrocyclic ligands through condensation with aldehydes. 2,6-Diaminopyridine can be used to synthesize the analgesic phenazopyridine hydrochloride (HY-B0985) .

HY-W009411

Dansyl hydrazine

Biochemical Assay Reagents

Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease .

HY-W005176

Methyl 3-oxohexanoate

Methyl Butyrylacetate; Methyl 3-oxohexanoate

Biochemical Assay Reagents

Methyl 3-oxohexanoate (Methyl Butyrylacetate) is an organic compound commonly used in the manufacture of fragrances, drugs, and other chemicals. It can be used as a condensation reagent, a diazotization reagent and an addition reagent, and it plays a catalytic role in some organic synthesis reactions, and can also play a role in some drug synthesis. In addition, the compound is widely used in the food industry, for example in products such as juices, beer and confectionery.

HY-W009048

Dicyclohexano-18-crown-6-ether

DCH18C6; Perhydrodibenzo-18-crown-6

Biochemical Assay Reagents

Dicyclohexano-18-crown-6-ether (DCH18C6) is an excellent strontium chelating agent. Dicyclohexano-18-crown-6-ether exhibits favorable extraction capacity and selectivity toward Sr (II). After chemical modification, Dicyclohexano-18-crown-6-ether is covalently bonded to an organosilicon matrix via co-condensation. DCH18C6-functionalized organosilicon materials are expected to be applied to the extraction and separation of strontium from radioactive waste liquid .

HY-134428

Arachidonoyl coenzyme A lithium	Biochemical Assay Reagents
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-W068214

Methyl undec-10-enoate Methyl-10-undecenoate	Biochemical Assay Reagents
Methyl undec-10-enoate, which is an ester formed by the condensation of methanol and undec-10-enoic acid, is commonly used as a flavoring and fragrance in the food and cosmetic industries due to its sweet fruity smell and taste , in addition, its potential use in biofuel production and as a starting material for the synthesis of various organic compounds was investigated.

HY-W015477

2-Chloro-6-fluorobenzaldehyde	Biochemical Assay Reagents
2-Chloro-6-fluorobenzaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. 2-Chloro-6-fluorobenzaldehyde can be used to synthesize methyl 2-cyano-3-dihalophenyl-2-propenoate through piperidine catalyzed Knoevenagel condensation reaction with methyl cyanoacetate .

HY-W099563

4-Nitrophenyl stearate

Biochemical Assay Reagents

4-Nitrophenyl stearate, which is an ester formed by the condensation of stearic acid and 4-nitrophenol, is commonly used as a substrate for enzymatic assays, where the hydrolysis of ester bonds by esterase and lipase can be measured by absorbance or ratio In addition, 4-Nitrophenyl stearate has been used as a model compound to study the enzymatic activity and selectivity of lipases and esterases from various sources. The long hydrophobic tail of the molecule makes it suitable for use in lipophilic Good solubility in the environment makes it a useful probe for studying lipid metabolism.

HY-Y0198R

2,6-Diaminopyridine (Standard)

Biochemical Assay Reagents

2,6-Diaminopyridine (Standard) is the analytical standard of 2,6-Diaminopyridine (HY-Y0198). This product is intended for research and analytical applications. 2,6-Diaminopyridine is an intermediate and coupling agent for hair dyes. 2,6-Diaminopyridine participates in organic synthesis reactions such as N-methylation and can bind metal ions by forming macrocyclic ligands through condensation with aldehydes. 2,6-Diaminopyridine can be used to synthesize the analgesic phenazopyridine hydrochloride (HY-B0985) .

HY-183003C

Mannose-PEG5000-COOH	Biochemical Assay Reagents
Mannose-PEG5000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183003D

Mannose-PEG10000-COOH	Biochemical Assay Reagents
Mannose-PEG10000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183003A

Mannose-PEG2000-COOH	Biochemical Assay Reagents
Mannose-PEG2000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183003

Mannose-PEG1000-COOH	Biochemical Assay Reagents
Mannose-PEG1000-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183003B

Mannose-PEG3400-COOH	Biochemical Assay Reagents
Mannose-PEG3400-COOH is a conjugate composed of mannose, PEG chains, and carboxyl groups (COOH). Mannose-PEG-COOH combines the targeting recognition ability of mannose with the carboxyl group, which can undergo condensation or esterification reactions with amino and hydroxyl groups, for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183163D

Glucose-PEG10000-COOH	Biochemical Assay Reagents
Glucose-PEG10000-COOH is a conjugate composed of glucose, PEG chains, and carboxyl groups (COOH). Glucose-PEG10000-COOH combines the targeting recognition ability of glucose with the carboxyl groups capable of condensation or esterification reactions with amino and hydroxyl groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183163B

Glucose-PEG3400-COOH	Biochemical Assay Reagents
Glucose-PEG3400-COOH is a conjugate composed of glucose, PEG chains, and carboxyl groups (COOH). Glucose-PEG3400-COOH combines the targeting recognition ability of glucose with the carboxyl groups capable of condensation or esterification reactions with amino and hydroxyl groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183163

Glucose-PEG1000-COOH	Biochemical Assay Reagents
Glucose-PEG1000-COOH is a conjugate composed of glucose, PEG chains, and carboxyl groups (COOH). Glucose-PEG1000-COOH combines the targeting recognition ability of glucose with the carboxyl groups capable of condensation or esterification reactions with amino and hydroxyl groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183163C

Glucose-PEG5000-COOH	Biochemical Assay Reagents
Glucose-PEG5000-COOH is a conjugate composed of glucose, PEG chains, and carboxyl groups (COOH). Glucose-PEG5000-COOH combines the targeting recognition ability of glucose with the carboxyl groups capable of condensation or esterification reactions with amino and hydroxyl groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

HY-183163A

Glucose-PEG2000-COOH	Biochemical Assay Reagents
Glucose-PEG2000-COOH is a conjugate composed of glucose, PEG chains, and carboxyl groups (COOH). Glucose-PEG2000-COOH combines the targeting recognition ability of glucose with the carboxyl groups capable of condensation or esterification reactions with amino and hydroxyl groups, making it suitable for applications such as targeted drug delivery systems and nanoparticle modification.

Cat. No.	Product Name	Target	Research Area

HY-N13356

L-gamma-Glutamyl-L-threonine gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr	Bacterial Peptide-Drug Conjugates (PDCs) Drug Metabolite	Infection Inflammation/Immunology
L-gamma-Glutamyl-L-threonine (gamma-Glutamylthreonine; H-γ-Glu-Thr-OH; γ-Glu-Thr) is a dipeptide obtained through the formal condensation of the L-glutamic acid side chain carboxyl group and the L-threonine amino group. L-gamma-Glutamyl-L-threonine is present in high concentrations in human urine and exhibits antibacterial activity against Gram-negative bacterial. L-gamma-Glutamyl-L-threonine is also a flavor compound. Gamma-Glutamylthreonine is a metabolite catalyzed by γ-glutamyl transpeptidase and is associated with immune regulation. Gamma-Glutamylthreonine can be used in research on inflammation and bacterial infections .

HY-P1743

Acyl Carrier Protein (ACP) (65-74)	Peptides	Infection
Acyl Carrier Protein (ACP) (65-74) is a key coenzyme fragment of fatty acid synthase (FAS) and participates in fatty acid synthesis as an acyl carrier. Acyl Carrier Protein (ACP) (65-74) mediates condensation, reduction and other cyclic reactions in fatty acid synthesis by covalently binding to acyl chains to form acyl-ACP intermediates, promoting acyl chain extension. Acyl Carrier Protein (ACP) (65-74) can regulate the synthesis ratio of saturated and unsaturated fatty acids. Acyl Carrier Protein (ACP) (65-74) can be used to study the mechanism of bacterial fatty acid synthesis and is a potential target for antibiotics (such as inhibiting the FAS system of pathogens) .

HY-W012572A

D-Histidine hydrochloride hydrate	Mitochondrial Metabolism Bacterial	Infection Metabolic Disease
D-Histidine hydrochloride hydrate is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine hydrochloride hydrate works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine hydrochloride hydrate downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine hydrochloride hydrate is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

HY-P11353

HA2 peptide	Small Interfering RNA (siRNA)	Cancer
HA2 peptide is a potent pH-responsive fusogenic peptide derived from hemagglutinin (HA). HA2 peptide is anionic and can be conjugated to cationic peptides for siRNA condensation. HA2 peptide can be used for the research of cancer .

HY-P11759

Myr-transportan-Cys	Drug Derivative	Cancer
Myr-transportan-Cys is a derivative of the cell-penetrating peptide Transportan (HY-P1732), and its conjugated myristoyl group (Myr) enhances the interaction between the peptide and cell membranes. Myr-transportan-Cys integrates three key delivery functions: nucleic acid condensation, cell penetration, and endosomal escape. Myr-transportan-Cys can form immunostimulatory tandem peptide nanocomplexes (iTPNCs) for encapsulating and delivering immunostimulatory oligonucleotide cargos to tumors .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-129905

L-Leucyl-L-Leucine methyl ester hydrochloride Maximum Cited Publications 18 Publications Verification LLOMe hydrochloride; Leu-Leu methyl ester hydrochloride; H-Leu-Leu-OMe hydrochloride	Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrochloride, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrochloride also can induce endolysosomal pathway stress .

HY-129905A

L-Leucyl-L-Leucine methyl ester hydrobromide Maximum Cited Publications 18 Publications Verification LLOMe hydrobromide; Leu-Leu methyl ester hydrobromide; H-Leu-Leu-OMe hydrobromide	Natural Products Classification of Application Fields Endogenous metabolite Inflammation/Immunology Disease Research Fields Source Classification	Endogenous Metabolite
L-Leucyl-L-Leucine methyl ester (LLOMe) hydrobromide, a dipeptide condensation product of L-leucine methyl ester generated by human monocytes or polymorphonuclear leukocytes, selectively eliminates lymphocytes with cytotoxic potential. L-Leucyl-L-Leucine methyl ester hydrobromide also can induce endolysosomal pathway stress .

HY-B1142

Lipoamide 5+ Cited Publications (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	NO Synthase
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-W012078

5-Methyl-2'-deoxycytidine 3 Publications Verification 5-Methyldeoxycytidine	Natural Products Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	DNA Methyltransferase Endogenous Metabolite
5-Methyl-2'-deoxycytidine (5mdC) is an endogenous substrate of DNA methyltransferases (such as mammalian 5-C-MTase) and binds to DNA dependent on the formation of DNA stem-loop structures. 5-Methyl-2'-deoxycytidine guides de novo DNA methylation by acting as a methylation mark and activates the methylation of adjacent CpG sites in single-stranded DNA through cis action. 5-Methyl-2'-deoxycytidine regulates DNA methylation patterns by recruiting methyltransferases to specific chromatin regions, affecting chromatin condensation and gene expression. Its distribution in plant cells is related to cell proliferation and differentiation stages. The methylation level of 5-Methyl-2'-deoxycytidine is low in proliferating cells and high in differentiated cells .

HY-W004289

Methyl pentadecanoate	Structural Classification other families Classification of Application Fields Other Diseases Plants Disease Research Fields Lipid Source Classification	Drug Derivative
Methyl pentadecanoate is a fatty acid ester that can be isolated from extracts of L. wallichi. Methyl pentadecanoate is formed by the condensation of the carboxyl group of pentadecanoic acid with the hydroxyl group of methanol .

HY-W012572

D-Histidine	Microorganisms Source Classification	Mitochondrial Metabolism Bacterial
D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

HY-N1915

Cellohexaose	Structural Classification Polysaccharides Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Saccharides Source Classification	Endogenous Metabolite
Cellohexaose is a glucose polymer with two or more glucose monomers produced from the breakdown of cellulose, consisting of a condensation of beta (1-4) linked D-glucose monomers .

HY-N2037C

(S)-Higenamine hydrobromide 1 Publications Verification (S)-Norcoclaurine hydrobromide	Alkaloids Classification of Application Fields Other Diseases Phenols Polyphenols Endogenous metabolite Isoquinoline Alkaloids Disease Research Fields Source Classification	Endogenous Metabolite
(S)-Higenamine ((S)-Norcoclaurine) hydrobromide, a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine hydrobromide is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N2592

Isobutylshikonin	Quinones Classification of Application Fields Phenols Polyphenols Plants Lithospermum canescens Lehm. Naphthalene Quinones Boraginaceae Inflammation/Immunology Disease Research Fields Source Classification	Others
Isobutylshikonin is a kind of shikonin pigments found in hairy root culture of Lithospermum canescens. Isobutylshikonin decreases cell viability induces marked changes in JA-4 cells with nuclear condensation and swelling in the presence of LPS (HY-D1056) .

HY-W102375

4-Acetoxycinnamic acid	Kaempferia galanga L. Classification of Application Fields Simple Phenylpropanols Phenylpropanoids Plants Inflammation/Immunology Disease Research Fields Source Classification Zingiberaceae	Drug Intermediate
4-Acetoxycinnamic acid is an acetate ester obtained by the formal condensation of the hydroxy group of trans-4-coumaric acid with acetic acid. 4-Acetoxycinnamic acid is a member of cinnamic acids and a member of phenyl acetates. 4-Acetoxycinnamic acid derives from a trans-4-coumaric acid .

HY-121199

Germanicol	Triterpenes Euphorbia boetica Terpenoids Euphorbiaceae Plants Source Classification	Apoptosis
Germanicol is a selective antineoplastic agent against human colon cancer cell lines HCT-116 and HT29 . Germanicol induces apoptosis via chromatin condensation and DNA damage .

HY-N7103R

Ethyl oleate (Standard)	Natural Products other families Classification of Application Fields Other Diseases Plants Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Endogenous Metabolite
Ethyl oleate (Standard) is the analytical standard of Ethyl oleate. This product is intended for research and analytical applications. Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .

HY-N2037B

(S)-Higenamine (S)-Norcoclaurine	Alkaloids Classification of Application Fields Other Diseases Phenols Polyphenols Endogenous metabolite Isoquinoline Alkaloids Disease Research Fields Source Classification	Endogenous Metabolite
(S)-Higenamine ((S)-Norcoclaurine), a S-enantiomer of Higenamine, is the entry compound in benzylisoquinoline alkaloid biosynthesis. (S)-Higenamine is produced by the condensation of dopamine and 4-hydroxyphenylacetaldehyde (4-HPAA) by norcoclaurine synthase (NCS) .

HY-N7497

Protoescigenin	Triterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-W012078R

5-Methyl-2'-deoxycytidine (Standard) 1 Publications Verification 5-Methyldeoxycytidine (Standard)	Structural Classification Natural Products Endogenous metabolite Source Classification	Reference Standards DNA Methyltransferase Endogenous Metabolite
5-Methyl-2'-deoxycytidine (5mdC) is an endogenous substrate of DNA methyltransferases (such as mammalian 5-C-MTase) and binds to DNA dependent on the formation of DNA stem-loop structures. 5-Methyl-2'-deoxycytidine guides de novo DNA methylation by acting as a methylation mark and activates the methylation of adjacent CpG sites in single-stranded DNA through cis action. 5-Methyl-2'-deoxycytidine regulates DNA methylation patterns by recruiting methyltransferases to specific chromatin regions, affecting chromatin condensation and gene expression. Its distribution in plant cells is related to cell proliferation and differentiation stages. The methylation level of 5-Methyl-2'-deoxycytidine is low in proliferating cells and high in differentiated cells .

HY-N7497R

Protoescigenin (Standard)	Triterpenes other families Terpenoids Plants Source Classification	Reference Standards Others
Protoescigenin (Standard) is the analytical standard of Protoescigenin. This product is intended for research and analytical applications. Protoescigenin is the main aglycone of horse chestnut saponin mixture known as escin. Protoescigenin is selected as substrate for exploratory chemistry towards selective protection, followed by propargyl ether formation and subsequent condensation with azido-monosaccharides, to obtain novel triazole linked conjugates of the triterpene .

HY-N8617

Trijuganone C	Quinones Structural Classification Labiatae Samanea saman (Jacq.) Merr. Benzene Quinones Plants Naphthalene Quinones Source Classification	DNA/RNA Synthesis Caspase PARP Bcl-2 Family Mitochondrial Metabolism Apoptosis
Trijuganone C is a tanshinone-type diterpenoid compound. Trijuganone C can be isolated from the roots of Salvia miltiorrhiza Bunge. Trijuganone C induces chromatin condensation, DNA fragmentation, activation of Caspase-3, -8 and -9, as well as cleavage of PARP. Trijuganone C activates Bid and Bax, leading to loss of mitochondrial membrane potential and inducing the release of cytochrome c from mitochondria into the cytosol. Trijuganone C exerts antiproliferative effects through Apoptosis induction mediated by Mitochondrial dysfunction and Caspase activation. Trijuganone C exhibits significant antiproliferative activity against leukemia cells and colon cancer cells .

HY-W012572R

D-Histidine (Standard)	Microorganisms Source Classification	Reference Standards Mitochondrial Metabolism Bacterial
D-Histidine (Standard) is the analytical standard of D-Histidine (HY-W012572). This product is intended for research and analytical applications. D-Histidine is an anti-biofilm agent that targets bacterial quorum sensing systems (such as RhlI/RhlR pathway) and has antibacterial activity. D-Histidine works by non-covalently binding to bacterial regulatory factors or copper ion complexes, selectively inhibiting bacterial biofilm formation and motility. D-Histidine downregulates quorum sensing-related gene expression, reduces the synthesis of virulence factors (such as alginate and proteases), and interferes with bacterial membrane stability, inhibiting biofilm formation, promoting the disintegration of mature biofilms, and enhancing antibiotic sensitivity. D-Histidine is also an efficient catalyst for the salt-induced peptide formation (SIPF) reaction, which promotes the condensation of amino acids to form dipeptides (such as dialanine and dilysine) by forming a complex with copper ions (Cu ²⁺) .

HY-N11764

β-Santalol	Structural Classification Natural Products Santalum spicatum A. DC. Plants Source Classification Santalaceae	Apoptosis Caspase
β-Santalol is a sesquiterpene alcohol with apoptosis (apoptosis)-inducing activity and cytotoxic activity. β-Santalol activates caspase-3, induces nuclear chromatin condensation, and promotes the formation of apoptotic bodies. β-Santalol targets cancer cells. β-Santalol can be used in research related to promyelocytic leukemia, lung adenocarcinoma, and oral squamous cell carcinoma .

HY-W004289R

Methyl pentadecanoate (Standard)	Structural Classification Natural Products other families Plants Source Classification	Reference Standards Others
Methyl pentadecanoate is a fatty acid ester, can be isolated from L. wallichi extracts. Methyl pentadecanoate is obtained by condensation of the carboxy group of pentadecanoic acid with the hydroxy group of methanol .

HY-141897

3-Deoxy-D-arabino-heptulosonate 7-phosphate	Structural Classification Natural Products Endogenous metabolite Source Classification	Nucleoside Antimetabolite/Analog
3-Deoxy-D-arabino-heptulosonate 7-phosphate is produced by the condensation of D-erythrose 4-phosphate with phosphoenolpyruvate (PEP), catalyzed by 3-deoxy-d-arabino-heptulosonate 7-phosphate (DAH 7-P) synthase (phe) .

HY-W102375R

4-Acetoxycinnamic acid (Standard)	Structural Classification Kaempferia galanga L. Simple Phenylpropanols Phenylpropanoids Plants Source Classification Zingiberaceae	Drug Intermediate Reference Standards
4-Acetoxycinnamic acid (Standard) is the analytical standard of 4-Acetoxycinnamic acid (HY-W102375). This product is intended for research and analytical applications. 4-Acetoxycinnamic acid is an acetate ester obtained by the formal condensation of the hydroxy group of trans-4-coumaric acid with acetic acid. 4-Acetoxycinnamic acid is a member of cinnamic acids and a member of phenyl acetates. 4-Acetoxycinnamic acid derives from a trans-4-coumaric acid .

HY-N13034

Diuvaretin	Structural Classification Monodora minor Engl. & Diels Phenols Polyphenols Plants Annonaceae Source Classification	Caspase Apoptosis Parasite
Diuvaretin is an antimalarial agent and a C-phenylated dihydrochalcone. Diuvaretin can be isolated from the roots of U. acuminata. Diuvaretin increases the activity of Caspase-3 and triggers Apoptosis. Diuvaretin exhibits antiparasitic activity against Plasmodium falciparum. Diuvaretin can be used in the research of promyelocytic leukemia and malaria .

Cat. No.	Product Name	Chemical Structure

HY-W740027

5-Methyl-2'-deoxycytidine-d3

5-Methyl-2'-deoxycytidine-d₃ (5-Methyldeoxycytidine-d₃) is the deuterium labeled Methyl-2'-deoxycytidine (HY-W012078). 5-Methyl-2'-deoxycytidine (5mdC) is an endogenous substrate of DNA methyltransferases (such as mammalian 5-C-MTase) and binds to DNA dependent on the formation of DNA stem-loop structures. 5-Methyl-2'-deoxycytidine guides de novo DNA methylation by acting as a methylation mark and activates the methylation of adjacent CpG sites in single-stranded DNA through cis action. 5-Methyl-2'-deoxycytidine regulates DNA methylation patterns by recruiting methyltransferases to specific chromatin regions, affecting chromatin condensation and gene expression. Its distribution in plant cells is related to cell proliferation and differentiation stages. The methylation level of 5-Methyl-2'-deoxycytidine is low in proliferating cells and high in differentiated cells .

HY-W011297S2

Methyl arachidonate-13C4
Methyl arachidonate- ¹³C₄ (Arachidonic acid methyl ester- ¹³C₄) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-W011297S3

Methyl arachidonate-13C5
Methyl arachidonate- ¹³C₅ (Arachidonic acid methyl ester- ¹³C₅) is ¹³C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite .

HY-W009411S

Dansyl hydrazine-13C2

Dansyl hydrazine- ¹³C₂ is the ¹³C-labeled Dansyl hydrazine (HY-W009411). Dansyl hydrazine is a carbohydrate-specific fluorescent dye (Ex/Em = 340 nm/525 nm). Dansyl hydrazine undergoes a condensation reaction with aldehyde groups generated by periodate oxidation on carbohydrate-containing structures to form fluorescent hydrazone compounds. Dansyl hydrazine selectively stains polysaccharides in formalin-fixed, paraffin-embedded human post-mortem brain tissues, revealing detailed structural features. Dansyl hydrazine is applicable to research related to Alzheimer's disease, Lafora disease, and polyglucosan body disease.

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P86979

	NCAPD2 Antibody (YA6672) 2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; 2810406C15Rik antibody; 2810465G24Rik antibody; CAP-D2 antibody; CAPD2 antibody; CEP2 antibody; CEP250 antibody; Chromosome condensation-related SMC-associated protein 1 antibody; Chromosome-associated protein D2 antibody; CNAP1 antibody; CND1 antibody; Condensin antibody; Condensin complex subunit 1 antibody; eg7 antibody; hCAP-D2 antibody; hCAPD2 antibody; KIAA0159 antibody; mKIAA0159 antibody; NCAPD2 antibody; non-SMC condensin I complex, subunit D2 antibody; XCAP D2 homolog antibody;	WB, ICC/IF, IHC-P	Human
	NCAPD2 Antibody (YA6672) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to NCAPD2.

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Cat. No.	Product Name		Classification

HY-N7103

Ethyl oleate		Solvents
Ethyl oleate is an orally active fatty acid ester formed from the condensation of oleic acid and ethanol. Ethyl oleate is the main fatty acid ethyl ester in the blood after alcohol ingestion. Ethyl oleate has no obvious toxicity to rats and its absorption, distribution and excretionare similar to triacylglycerol. Ethyl oleate can accelerate the drying process of certain foods and can also be used as a liquid lipid component in nanostructured lipid carriers .

HY-155882

mPEG750-amine mPEG750-NH2		Polymers
mPEG750-amine (mPEG750-NH2) is a chemical modification reagent for nanoparticles, capable of covalently binding to Ad-PVA to form Ad-PVA-PEG polymers. mPEG750-amine stabilizes gene delivery complexes by providing steric hindrance, reducing particle aggregation, while enhancing the water solubility and serum stability of the complex, reducing carrier cytotoxicity, and assisting in the efficient condensation of pDNA by cationic components to form nanoparticles that can be endocytosed by cells. mPEG750-amine can also be used to synthesize folate-conjugated polymer micelles for encapsulating the anticancer agent Camptothecin (HY-16560). Folate-conjugated polymer micelles are effective carriers for poorly soluble anticancer drugs, capable of avoiding macrophages and acting through folate receptor (FR)-mediated endocytosis to target tumor cells. mPEG750-amine can be applied to research in the field of non-viral gene delivery, as a component of gene delivery vectors, facilitating the safe and efficient delivery of nucleic acid drugs to target cells .

HY-W011548

2-Aminoadenosine		Nucleoside Analogs Adenosine
2-Aminoadenosine is a modified adenine base and adenosine analog that stabilizes RNA duplexes and enhances template-directed nucleotide condensation reactions. 2-Aminoadenosine forms three hydrogen bonds with uracil to increase the melting temperature of hybrid strands, thereby stabilizing uracil-containing RNA duplexes .

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condensation

Inhibitors & Agonists

Screening Libraries

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

NaturalProducts

Isotope-Labeled Compounds

Antibodies

Oligonucleotides

Natural
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