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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
cytosolic isoform
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "cytosolic isoform" in MCE Product Catalog:
3
3 Cited Publications
(Rac)-SHIN2 is a pyrazolopyran derivative and a serine hydroxymethyltransferase (SHMT) inhibitor. (Rac)-SHIN2 has antibacterial activity and low cytotoxicity against Hep2 cells. (Rac)-SHIN2 exerts potent antibacterial activity against both vancomycin-susceptible and vanA-type vancomycin-resistant Enterococcus .
1
1 Cited Publications
Cat. No.: HY-18540
CAS No.: 1402612-55-8
Research Areas:
KT109 is a potent and an isoform-selective inhibitor of diacylglycerol lipase-β (DAGLβ) with an IC50 of 42 nM. KT109 has ~60-fold selectivity for DAGLβ over DAGLα. KT109 shows inhibitory activity against PLA2G7 (IC50=1 µM). KT109 shows negligible activity against FAAH, MGLL, ABHD11, and cytosolic phospholipase A2 (cPLA2 or PLA2G4A). KT109 perturbs a lipid network involved in macrophage inflammatory responses and lowers 2-Arachidonoylglycerol (HY-W011051), Arachidonic acid (HY-109590) and eicosanoids in mouse peritoneal macrophages .
Cat. No.: HY-156181
CAS No.: 59994-64-8
Target:
Research Areas:
hCAIX/XII-IN-8 (compound 3g) is a potent human (carbonic anhydrase) CA IX and XII inhibitor, with Ki values of 8.5 and 6.7 nM, respectively. hCAIX/XII-IN-8 shows particularly strong inhibitory activity against the tumor-associated membrane-bound isoforms, hCA IX and XII, while maintaining a high selectivity ratio over cytosolic off-target isoforms hCA I and II .
Cat. No.: HY-P74656
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: NCF2; Chronic Granulomatous Disease, Autosomal 2; Neutrophil cytosolic Factor 2; 67 KDa Neutrophil Oxidase Factor; NOXA2; NCF-2; Neutrophil NADPH Oxidase Factor 2; Neutrophil cytosolic Factor 2 isoform 3; Neutrophil Cytosol Factor 2; P67-PHOX; NADPH Oxida
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P74655
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NCF2; Chronic Granulomatous Disease, Autosomal 2; Neutrophil cytosolic Factor 2; 67 KDa Neutrophil Oxidase Factor; NOXA2; NCF-2; Neutrophil NADPH Oxidase Factor 2; Neutrophil cytosolic Factor 2 isoform 3; Neutrophil Cytosol Factor 2; P67-PHOX; NADPH Oxida
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P71661
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: RUVBL2; RuvB-Like 2; RuvB Like AAA ATPase 2; TAP54-Beta; TIP49b; Reptin52; INO80J; Reptin; TIP48; ECP-51; INO80 Complex Subunit J; Erythrocyte cytosolic Protein, 51-KD; ECP51; RuvB-Like 2 (E. Coli), isoform CRA_b; RVB2; RuvB-Like 2 (E. Coli), isoform CRA_
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
