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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
cytosolic phospholipase A2 alpha
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "cytosolic phospholipase A2 alpha" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-18540
CAS No.: 1402612-55-8
Research Areas:
KT109 is a potent and an isoform-selective inhibitor of diacylglycerol lipase-β (DAGLβ) with an IC50 of 42 nM. KT109 has ~60-fold selectivity for DAGLβ over DAGLα. KT109 shows inhibitory activity against PLA2G7 (IC50=1 µM). KT109 shows negligible activity against FAAH, MGLL, ABHD11, and cytosolic phospholipase A2 (cPLA2 or PLA2G4A). KT109 perturbs a lipid network involved in macrophage inflammatory responses and lowers 2-Arachidonoylglycerol (HY-W011051), Arachidonic acid (HY-109590) and eicosanoids in mouse peritoneal macrophages .
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Research Areas:
CAY10502 is a potent, calcium-dependent cytosolic phospholipase A2 α (cPLA2α) inhibitor with an IC50 of 4.3 nM for isolated enzyme. CAY10502 can be used in the research of retinopathy and inflammatory diseases .
Cat. No.: HY-119094
CAS No.: 540523-42-0
Target:
Research Areas:
WAY-196025 is a selective and orally active indole cytosolic phospholipase A2 alpha (cPLA2α) inhibitor with an IC50 of 0.01μM and a Kd of 0.013 μM. WAY-196025 can inhibit the production of prostaglandins (such as PGE2) and leukotrienes (such as LTB4), and reduce the release of inflammatory mediators. WAY-196025 can be used for the researches of inflammation and immunology, such as asthma .
Cat. No.: HY-P87025
Synonyms: Calcium dependent phospholipid binding protein antibody; CPLA 2 antibody; cPLA2 alpha antibody; cPLA2 antibody; cytosolic phospholipase A2 antibody; cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; Phosphatidylcholine 2 acylhydrolase antibody; Calcium dependent phospholipid binding protein antibody; CPLA 2 antibody; cPLA2 alpha antibody; cPLA2 antibody; cytosolic phospholipase A2 antibody; cytosolic phospholipase A2 group IVA antibody; Lysophospholipase antibody; MGC126350 antibody; PA24A_HUMAN antibody; Phosphatidylcholine 2 acylhydrolase antibody; Phosphatidylcholine 2-acylhydrolase antibody; phospholipase A2 group 4 A antibody; phospholipase A2 group IVA (cytosolic calcium dependent) antibody; phospholipase A2 group IVA antibody; phospholipaseA2 antibody; PLA2G4 antibody; plA2g4a antibody;
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
