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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
54 Results for "
dermatophytes
" in MedChemExpress (MCE) Product Catalog:
Products (54)
54 Results for "dermatophytes" in MCE Product Catalog:
11
Target:
Research Areas:
Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect .
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11 Publications Verification
Cat. No.: HY-B0450A
CAS No.: 41621-49-2
Synonyms: Ciclopirox ethanolamine; HOE 296
Target:
Ciclopirox olamine (Ciclopirox ethanolamine) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox olamine also has anticancer and anti-inflammatory effect .
4
Tioconazole (UK-20349) is a broad-spectrum antifungal imidazole derivative. Tioconazole inhibits several dermatophytes and yeasts, with MIC50 values of less than 3.12 mg/L and 9 mg/L, respectively. Additionally, Tioconazole exhibits anti-parasitic activity. Tioconazole exerts anticancer activity by inhibiting the PI3K/AKT/mTOR signaling pathway and blocking autophagy. Tioconazole is applicable for research in the fields of anti-infection and anticancer therapy .
2
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Oteseconazole (VT-1161) is a potent and orally active anti-fungal agent. Oteseconazole potently binds to and inhibits Candida albicans cytochrome P45051 (CYP51) activity (Kd ≤39 nM), shows no obvious effect on human CYP51. Oteseconazole also can be used for the research of dermatophytes .
2
Efinaconazole (KP-103) is a triazole antifungal agent and againsts T. mentagrophytes SM-110 and C. albicans ATCC 10231 with MICs of 0.0039 μg/mL and 0.00098 μg/mL, respectively . Efinaconazole has a potent in vitro activity against fungal pathogens including dermatophytes, Candida and Malassezia species .
1
Sulbentine (Dibenzthione) is a thiadiazine-class antifungal agent. Sulbentine exhibits fungicidal and fungistatic activity against Trichophyton mentagrophytes. Sulbentine can be used for the research of dermatophyte infection .
Cat. No.: HY-B0518A
CAS No.: 65473-14-5
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Research Areas:
Naftifine hydrochloride is an antibiotic. Naftifine hydrochloride has antifungal activity against dermatophytes, aspergilli, Sporothrix schenckii, and yeasts of the genus Candida. Naftifine hydrochloride can be used for the research of superficial dermatomycoses inhibition .
Synonyms: BAY-W-6341
Abafungin (BAY-W-6341) is a broad-spectrum fungicidal arylguanidine compound and a selective inhibitor of sterol-C-24-methyltransferase. Abafungin blocks the transmethylation reaction at the C-24 position of the sterol side chain during the ergosterol biosynthesis pathway. Abafungin directly disrupts fungal cell membrane integrity, and diminishes fungal viability independent of the fungal growth state. Abafungin can be applied to the research of fungal infections, particularly dermatomycoses .
Cat. No.: HY-B0348
CAS No.: 88678-31-3
Synonyms: Piritetrate; M-732
Liranaftate (Piritetrate) is a squalene epoxidase inhibitor with anti-fungicidal activities. Liranaftate can be used for the research of dermatophytes. Liranaftate also suppresses fungal element-promoted production of IL-8 and experimental inflammation .
Category:
Infection Triterpenes Herniaria glabra Linnaeus. Terpenoids Plants Disease Research Fields Caryophyllaceae
Target:
Cat. No.: HY-W984782
CAS No.: 523-64-8
ME1111 is an antifungal agent that is active against dermatophytes. ME1111 is an inhibitor of the succinate dehydrogenase of Trichophyton species. ME1111 has an excellent ability to penetrate human nails and is used for onychomycosis research .
Synonyms: KP-103-d4
Cat. No.: HY-114518
CAS No.: 101828-21-1
Synonyms: KP363
Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent . Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as tinea pedis, tinea cruris, tinea versicolor .
Cat. No.: HY-N11546
CAS No.: 30994-75-3
Target:
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Antifungal agent 18 is an antifungal agent. Antifungal agent 18 shows a broad-spectrum antifungal activity against major human fungal pathogens. Antifungal agent 18 compromises fungal cell wall integrity by targeting the unfolded protein response (UPR), calcineurin, and MAPK pathways. Antifungal agent 18 shows antifungal activity in virto and vivo. Antifungal agent 18 can be used for the research of invasive fungal pathogens and cutaneous dermatophytes .
Cat. No.: HY-171796
CAS No.: 101023-71-6
Bromomonilicin is a selective fungal cell membrane inhibitor. Bromomonilicin exerts antifungal activity by disrupting fungal cell membrane integrity. Bromomonilicin is promising for research of plant pathogenic fungal infections (e.g., Monilinia fructicola-induced brown rot) and superficial mycoses (e.g., dermatophyte infections) .
Cat. No.: HY-B0450S1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
