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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
deuterated analog
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "deuterated analog" in MCE Product Catalog:
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1 Cited Publications
Cat. No.: HY-50856S
CAS No.: 1513883-39-0
Synonyms: CTP-543; Ruxolitinib-d8; INCB18424-d8
Target:
Research Areas:
Deuruxolitinib (CTP-543; Ruxolitinib-d8) is a deuterated analog of Ruxolitinib (HY-50856) and an orally active, selective inhibitor of JAK1 and JAK2. Deuruxolitinib blocks Janus kinase-mediated cytokine receptor signaling and proinflammatory cytokine gene expression. Deuruxolitinib is primarily metabolized in the liver via CYP2C9. Deuruxolitinib promotes scalp hair regrowth in severe chronic alopecia areata. Deuruxolitinib is used in alopecia areata-related research .
Cat. No.: HY-W759404
Synonyms: Cortexolone 17 alpha-propionate-d5; Cortexolone 17α-propionate-d5; CB-03-01-d5
Cat. No.: HY-101411S
Synonyms: N-acetyl GABA-d3
Cat. No.: HY-100442S1
Purity: 98.19%
Synonyms: ABR-215757-d5-1; ABR 25757-d5-1
Cat. No.: HY-13017S1
CAS No.: 1413431-22-7
Synonyms: VX-770-d19
Cat. No.: HY-15285
CAS No.: 2070009-32-2
Cat. No.: HY-100442S
Synonyms: ABR-215757-d5; ABR 25757-d5
Synonyms: NA-Gly-d8
Cat. No.: HY-138615S5
CAS No.: 2687960-74-1
Synonyms: dTTP-d15 dilithium
Target:
Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Research Areas:
Deoxythymidine-5'-triphosphate-d15 dilithium (dTTP-d15 dilithium) is the deuterated-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia .
Cat. No.: HY-169984S
CAS No.: 1771691-32-7
Cat. No.: HY-138615S3
Synonyms: dTTP-15N2,d15 dilithium
Target:
Isotope-Labeled Compounds DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Endogenous Metabolite
Research Areas:
Deoxythymidine-5'-triphosphate- 15N2,d15 dilithium (dTTP- 15N2,d15 dilithium) is the deuterated, 15N-labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is a deoxyribonucleoside triphosphate and a thymidine analog, which serves as a direct precursor for DNA synthesis. Deoxythymidine-5'-triphosphate can be used for DNA amplification in the DNA polymerase chain reaction (PCR). Deoxythymidine-5'-triphosphate is also applicable to research related to diseases such as leukemia .
Cat. No.: HY-174353
Target:
Research Areas:
CYP51-IN-22, the non-deuterated analog of CYP51-IN-23-d3 (HY-174353S), is a potent and broad-spectrum CYP51 inhibitor.CYP51-IN-22 inhibits Aspergillus fumigatum with a MIC80 of 1 μg/mL. CYP51-IN-22 can prevent fungal phase transformation and biofilm formation. CYP51-IN-22 exhibits anti-drug resistance activity and fungal activity, and shows excellent safety for cells and significant pharmacological activity in mice. CYP51-IN-22 can be used for the study of invasive fungal infections (IFIs) .
Cat. No.: HY-131501S
Cat. No.: HY-W009538S
Synonyms: 5-Fluoro-5'-deoxycytidine-d3
Cat. No.: HY-42484S
Synonyms: Eribulin intermediate-d3
Research Areas:
ER-076349-d3 (Eribulin intermediate-d3) is the deuterated-labeled ER-076349 (HY-42484). ER-076349 (Eribulin intermediate) is an inhibitor of tubulin polymerization, induces G2-M cell cycle arrest, and disrupts mitotic spindles. ER-076349 inhibits cancer cell growth, and inhibits tumor growth in several human tumor xenografts. ER-076349 is an analog of Halichondrin B.
Cat. No.: HY-50856BS
CAS No.: 2147706-60-1
Synonyms: CTP-543 phosphate; Ruxolitinib-d8 phosphate; INCB18424-d8 (phospha
Target:
Research Areas:
Deuruxolitinib phosphate (CTP-543 phosphate; Ruxolitinib-d8 phosphate) is a deuterated analog of Ruxolitinib (HY-50856) and an orally active, selective inhibitor of JAK1 and JAK2. Deuruxolitinib phosphate blocks Janus kinase-mediated cytokine receptor signaling and proinflammatory cytokine gene expression. Deuruxolitinib phosphate is primarily metabolized in the liver via CYP2C9. Deuruxolitinib phosphate promotes scalp hair regrowth in severe chronic alopecia areata. Deuruxolitinib phosphate is used in alopecia areata-related research .
Cat. No.: HY-160099S
Synonyms: WIT003-d2
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
